MLCK inhibitor peptide 18
Selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable.
(Modifications: Lys-9 = C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in water|
References are publications that support the biological activity of the product.
Lukas et al (1999) Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge. J.Med.Chem. 42 910 PMID: 10072688
Zolotarevsky et al (2002) A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. Gastroenterology 123 163 PMID: 12105845
If you know of a relevant reference for MLCK inhibitor peptide 18, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: MLCK Inhibitor Peptide 18, MLCK Inhibitor Peptide 18 supplier, Selective, inhibitors, inhibits, myosin, light, chain, kinases, MLCK, Inhibitor, Peptide18, Myosin, Light, Chain, Kinase, Peptide, 18, Calcium, Binding, Protein, 1885, Tocris Bioscience
1 Citation for MLCK inhibitor peptide 18
Citations are publications that use Tocris products. Selected citations for MLCK inhibitor peptide 18 include:
Wang et al (2012) Inhibition of TNF-α improves the bladder dysfunction that is associated with type 2 diabetes. Proc Natl Acad Sci U S A 61 2134 PMID: 22688336
Do you know of a great paper that uses MLCK inhibitor peptide 18 from Tocris? Please let us know.
Reviews for MLCK inhibitor peptide 18
There are currently no reviews for this product. Be the first to review MLCK inhibitor peptide 18 and earn rewards!
Have you used MLCK inhibitor peptide 18?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.