MCH (human, mouse, rat)
Potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 receptors respectively). Increases food intake in vivo.
(Modifications: Disulfide bridge between 7-16)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 2386.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.42 mL||2.09 mL||4.19 mL|
|5 mM||0.08 mL||0.42 mL||0.84 mL|
|10 mM||0.04 mL||0.21 mL||0.42 mL|
|50 mM||0.01 mL||0.04 mL||0.08 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
If you know of a relevant reference for MCH (human, mouse, rat), please let us know.
View Related Products by Product Action
Keywords: MCH (human, mouse, rat), supplier, potent, endogenous, MCH, agonists, receptors, melanin-concentration, hormone, MCH1, MCH2, MCH2R, MCHR2, MCH1R, MCHR1, Melanin-concentrating, Melanin, concentrating, concentration, Melanin-concentrating, hormone, (human,, mouse,, rat), Melanin-concentrating, Hormone, Receptors, Melanin-concentrating, Hormone, Receptors, Tocris Bioscience
Citations for MCH (human, mouse, rat)
Citations are publications that use Tocris products.
Currently there are no citations for MCH (human, mouse, rat). Do you know of a great paper that uses MCH (human, mouse, rat) from Tocris? If so please let us know.
Literature in this Area
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.