Potent and selective hCXCR6 antagonist (IC50 = 140 nM); 100-fold less active at the murine CXCR6 receptor (IC50 = 18 μM). Exhibits selectivity over CXCR5, CXCR4, CCR6 and APJ receptors (IC50 >79 μM).
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 502. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.99 mL||9.96 mL||19.92 mL|
|5 mM||0.4 mL||1.99 mL||3.98 mL|
|10 mM||0.2 mL||1 mL||1.99 mL|
|50 mM||0.04 mL||0.2 mL||0.4 mL|
References are publications that support the biological activity of the product.
Hershberger et al (2012) Probing the CXCR6/CXCL16 Axis: targeting prevention of prostate cancer metastasis. Probe Reports from the NIH Molecular Libraries Program PMID: 24049849
If you know of a relevant reference for ML 339, please let us know.
View Related Products by Product Action
Keywords: ML 339, ML 339 supplier, ML339, Potent, human, CXCR6, antagonists, antagonism, metastasis, Chemokine, CXC, Receptors, 5943, Tocris Bioscience
Citations for ML 339
Citations are publications that use Tocris products.
Currently there are no citations for ML 339. Do you know of a great paper that uses ML 339 from Tocris? Please let us know.
Reviews for ML 339
There are currently no reviews for this product. Be the first to review ML 339 and earn rewards!
Have you used ML 339?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.