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Biological Activity for MRS 2905
MRS 2905 is a potent and selective P2Y14 receptor agonist (EC50 = 0.92 nM). Exhibits >2000-fold selectivity over P2Y6.
Technical Data for MRS 2905
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for MRS 2905
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for MRS 2905
The following data is based on the product molecular weight 484.2. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.45 mM||4.59 mL||22.95 mL||45.89 mL|
|2.25 mM||0.92 mL||4.59 mL||9.18 mL|
|4.5 mM||0.46 mL||2.29 mL||4.59 mL|
|22.5 mM||0.09 mL||0.46 mL||0.92 mL|
References for MRS 2905
References are publications that support the biological activity of the product.
Das et al (2010) Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups J.Med.Chem. 53 471 PMID: 19902968
Lazarowski et al (2015) UDP-sugars as extracellular signaling molecules: cellular and physiologic consequences of P2Y14 receptor activation. Mol.Pharmacol. 88 151 PMID: 25829059
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Keywords: MRS 2905, MRS 2905 supplier, MRS2905, Potent, selective, P2Y14, receptors, agonists, agonism, Purinergic, P2Y, Receptors, 5633, Tocris Bioscience
Citations for MRS 2905
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Literature in this Area
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