±-MF 094

Pricing Availability   Qty
Cat.No. 6718 - (±)-MF 094 | C30H37N3O4S
Description: Selective USP30 inhibitor
Chemical Name: N-(1-((5-(N-(tert-Butyl)sulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclohexanecarboxamide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews

Biological Activity for ±-MF 094

±-MF 904 is the racemate of MF 904, the S-enantiomer. The S-enantiomer is a selective USP30 (ubiquitin-specific-processing protease 30) inhibitor. MF 094 increases protein ubiquitination and inhibits mitophagy.

Technical Data for ±-MF 094

M. Wt 535.7
Formula C30H37N3O4S
Storage Store at -20°C
Purity ≥98% (HPLC)
PubChem ID 146503417
InChI Key DQXORJHBZHLLTE-UHFFFAOYSA-N
Smiles CC(C)(NS(=O)(C1=CC=CC2=C1C=CC=C2NC(C(NC(C3CCCCC3)=O)CC4=CC=CC=C4)=O)=O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for ±-MF 094

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 26.78 50

Preparing Stock Solutions for ±-MF 094

The following data is based on the product molecular weight 535.7. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.73 mL 18.67 mL 37.33 mL
2.5 mM 0.75 mL 3.73 mL 7.47 mL
5 mM 0.37 mL 1.87 mL 3.73 mL
25 mM 0.07 mL 0.37 mL 0.75 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References for ±-MF 094

References are publications that support the biological activity of the product.

Kluge et al (2018) Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg.Med.Chem.Lett. 28 2655 PMID: 29935771

Li and Liu et al (2020) Recent advances in the development of ubiquitin-specific-processing protease 7 (USP7) inhibitors. Eur.J.Med.Chem. 191 112107 PMID: 32092586


If you know of a relevant reference for ±-MF 094, please let us know.

View Related Products by Product Action

View all Deubiquitinating Enzyme Inhibitors

Keywords: (±)-MF 094, (±)-MF 094 supplier, MF094, racemate, USP30, inhibitors, inhibits, selective, ubiquitin, carboxyl-terminal, hydrolase, specific-processing, protease, mitophagy, ubiquitination, Deubiquitinating, Enzymes, 6718, Tocris Bioscience

Citations for ±-MF 094

Citations are publications that use Tocris products.

Currently there are no citations for ±-MF 094. Do you know of a great paper that uses ±-MF 094 from Tocris? Please let us know.

Reviews for ±-MF 094

There are currently no reviews for this product. Be the first to review ±-MF 094 and earn rewards!

Have you used ±-MF 094?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review