MRS 2768 tetrasodium salt
Selective P2Y2 agonist (EC50 = 1.89 μM). Displays no affinity for human P2Y4 or P2Y6 receptors.
|Storage||Store at -80°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in water (supplied pre-dissolved at a concentration of 10mM)|
Preparing Stock Solutions
The following data is based on the product molecular weight 728.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.37 mL||6.87 mL||13.73 mL|
|5 mM||0.27 mL||1.37 mL||2.75 mL|
|10 mM||0.14 mL||0.69 mL||1.37 mL|
|50 mM||0.03 mL||0.14 mL||0.27 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Ko et al (2008) Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorg.Med.Chem. 16 6319 PMID: 18514530
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Keywords: MRS 2768 tetrasodium salt, supplier, selective, P2Y2, agonists, purinergic, receptors, MRS2768, Purinergic, P2Y, Receptors, Purinergic, P2Y, Receptors, Tocris Bioscience
3 Citations for MRS 2768 tetrasodium salt
Citations are publications that use Tocris products. Selected citations for MRS 2768 tetrasodium salt include:
Ilatovskaya et al (2013) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol 305 C1050 PMID: 24048730
Shabir et al (2013) Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium. PLoS Comput Biol 305 F396 PMID: 23720349
Trabanelli et al (2012) Extracellular ATP exerts opposite effects on activated and regulatory CD4+ T cells via purinergic P2 receptor activation. J Immunol 189 1303 PMID: 22753942
Do you know of a great paper that uses MRS 2768 tetrasodium salt from Tocris? If so please let us know.