Narcotic opioid analgesic.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 321.8. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||6.22 mL||31.08 mL||62.15 mL|
|2.5 mM||1.24 mL||6.22 mL||12.43 mL|
|5 mM||0.62 mL||3.11 mL||6.22 mL|
|25 mM||0.12 mL||0.62 mL||1.24 mL|
References are publications that support the biological activity of the product.
Merck Index 12 1074
If you know of a relevant reference for Morphine hydrochloride, please let us know.
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Keywords: Morphine hydrochloride, Morphine hydrochloride supplier, opioid, receptors, analgesic, Miscellaneous/Non-selective, Opioids, 5158, Tocris Bioscience
2 Citations for Morphine hydrochloride
Citations are publications that use Tocris products. Selected citations for Morphine hydrochloride include:
Prather et al (2013) CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen. Biochem Biophys Res Commun 441 339 PMID: 24148245
Rajasekaran et al (2013) Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors. Toxicol Appl Pharmacol 269 100 PMID: 23537664
Do you know of a great paper that uses Morphine hydrochloride from Tocris? Please let us know.
Reviews for Morphine hydrochloride
Average Rating: 5 (Based on 1 Review.)
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Saline or morphine (10 mg/kg, s.c.) was injected 1 h prior to intrarectal instillation of peanut oil (Veh) or AITC 2% (v/v) in mice. Phosphorylation of p42/44 was analysed in spinal cord (Sc), thalamus (Th), hypothalamus (Hth), amygdala (Amy), and prefrontal cortex (Pfc) lysates using Western blot. Morphine significantly inhibited AITC-induced pp42/44 expression (shown in Image).
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.