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Mag-Fura-2 AM New
Biological Activity for Mag-Fura-2 AM
Mag-Fura-2 AM is a cell-permeable fluorescent magnesium ion (Mg2+) indicator. It shows selectivity for Mg2+ over other bivalent ions (Zn2+, Cu2+ and Ca2+). It exhibits >13,000-fold selectivity for Mg2+ ions over Ca2+ ions (Mg2+ Kd = 1.9 nM vs Ca2+ Kd = 25 μM). Excitation and emission maxima (λ) are 369 and 511 nm, respectively. Mag-Fura-2 AM can be used as an indirect indicator of ATP consumption/production.
It is recommended to prepare stock solutions in DMSO.
Optical Data for Mag-Fura-2 AM
|Extinction Coefficient (ε)||31000 M-1cm-1|
|Application||Confocal Imaging, Flow Cytometry|
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.Spectral Viewer
Technical Data for Mag-Fura-2 AM
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for Mag-Fura-2 AM
References are publications that support the biological activity of the product.
Schütz et al (2021) Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos. Cell Rep. 37 109851 PMID: 34686339
Watanabe et al (2022) Chronic magnesium deficiency causes reversible mitochondrial permeability transition pore opening and impairs hypoxia tolerance in the rat heart. J.Pharmacol.Sci. 148 238 PMID: 35063139
Cheng et al (2021) Variability of mitochondrial energy balance across brain regions. J.Neurochem. 157 1234 PMID: 33190229
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Citations for Mag-Fura-2 AM
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Fluorescent Dyes and Probes Research Product Guide
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