Mag-Fura-2 AM

Pricing Availability   Qty
Description: Magnesium (Mg2+) indicator, membrane permeable
Chemical Name: Bis(acetoxymethyl) 2,2'-((5-(2-(acetoxymethoxy)-2-oxoethoxy)-2-(5-((acetoxymethoxy)carbonyl)oxazol-2-yl)benzofuran-6-yl)azanediyl)diacetate
Purity: ≥95% (HPLC)
Literature (1)

Biological Activity for Mag-Fura-2 AM

Mag-Fura-2 AM is a cell-permeable fluorescent magnesium ion (Mg2+) indicator. It shows selectivity for Mg2+ over other bivalent ions (Zn2+, Cu2+ and Ca2+). It exhibits >13,000-fold selectivity for Mg2+ ions over Ca2+ ions (Mg2+ Kd = 1.9 nM vs Ca2+ Kd = 25 μM). Excitation and emission maxima (λ) are 369 and 511 nm, respectively. Mag-Fura-2 AM can be used as an indirect indicator of ATP consumption/production.

It is recommended to prepare stock solutions in DMSO.

Optical Data for Mag-Fura-2 AM

λabs 369 nm
λem 511 nm
Extinction Coefficient (ε) 31000 M-1cm-1
Cell Permeable Yes
Application Confocal Imaging, Flow Cytometry

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Technical Data for Mag-Fura-2 AM

M. Wt 722.57
Formula C30H30N2O19
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 130100-20-8
PubChem ID 131176
Smiles O=C(C1=CN=C(C2=CC3=C(C=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OCC(OCOC(C)=O)=O)=C3)O2)O1)OCOC(C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Mag-Fura-2 AM

References for Mag-Fura-2 AM

References are publications that support the biological activity of the product.

Schütz et al (2021) Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos. Cell Rep. 37 109851 PMID: 34686339

Watanabe et al (2022) Chronic magnesium deficiency causes reversible mitochondrial permeability transition pore opening and impairs hypoxia tolerance in the rat heart. J.Pharmacol.Sci. 148 238 PMID: 35063139

Cheng et al (2021) Variability of mitochondrial energy balance across brain regions. J.Neurochem. 157 1234 PMID: 33190229

If you know of a relevant reference for Mag-Fura-2 AM, please let us know.

Keywords: Mag-Fura-2 AM, Mag-Fura-2 AM supplier, membrane, permeable, fluorescent, probe, fluorescein, detection, fluorescence, indicators, and, sensors, Mg, ions, intracellular, magnesium, Fluorescent, Ion, Indicators, 7855, Tocris Bioscience

Citations for Mag-Fura-2 AM

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

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