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α,β-Methyleneadenosine 5'-triphosphate trisodium salt is a P2-purinoceptor agonist. Also shown to inhibit adenylate cyclase (Ki = 0.5 mM).
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 571.15. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.75 mL||8.75 mL||17.51 mL|
|5 mM||0.35 mL||1.75 mL||3.5 mL|
|10 mM||0.18 mL||0.88 mL||1.75 mL|
|50 mM||0.04 mL||0.18 mL||0.35 mL|
References are publications that support the biological activity of the product.
Krug et al (1973) α,β-Methylene-adenosine 5'-triphosphate. J.Biol.Chem. 248 1203 PMID: 4686923
Burnstock and Kennedy (1985) Is there a basis for distinguishing two types of P2-purinoceptor? Gen.Pharmacol 16 433 PMID: 2996968
If you know of a relevant reference for α,β-Methyleneadenosine 5'-triphosphate trisodium salt, please let us know.
Keywords: alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt, alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt supplier, P2, agonists, P2-purinoceptor, P2Y, Receptors, Purinergic, P2X, purinoceptors, α, β-Methyleneadenosines, alpha,beta-Methyleneadenosines, 5-triphosphate, trisodium, salt, a,b-Methyleneadenosine, a,b-meATP, 3209, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for α,β-Methyleneadenosine 5'-triphosphate trisodium salt include:
Palygin et al (2018) Characterization of purinergic receptor expression in ARPKD cystic epithelia. Purinergic Signal 14 485 PMID: 30417216
Haanes and Edvinsson (2014) Expression and characterization of purinergic receptors in rat middle meningeal artery-potential role in migraine. PLoS One 9 e108782 PMID: 25265286
Do you know of a great paper that uses α,β-Methyleneadenosine 5'-triphosphate trisodium salt from Tocris? Please let us know.
Average Rating: 4 (Based on 1 Review.)
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P2X1 and P2X3 agonist, the product works as expected.
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