α,β-Methyleneadenosine 5'-triphosphate trisodium salt

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Cat.No. 3209 - alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt | C11H15N5Na3O12P3 | CAS No. 1343364-54-4
Description: Non-selective P2 agonist
Chemical Name: α,β-Methyleneadenosine 5'-triphosphate trisodium salt
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Reviews (1)
Literature

Biological Activity

P2-purinoceptor agonist. Also shown to inhibit adenylate cyclase (Ki = 0.5 mM).

Technical Data

M. Wt 571.15
Formula C11H15N5Na3O12P3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1343364-54-4
PubChem ID 90488813
InChI Key CBAGKCWFSRTVER-MTQUBGKESA-K
Smiles O[C@@H]1[C@@H](COP(CP([O-])(OP([O-])(O)=O)=O)([O-])=O)O[C@@H](N3C2=NC=NC(N)=C2N=C3)[C@@H]1O.[Na+].[Na+].[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 57.12 100

Preparing Stock Solutions

The following data is based on the product molecular weight 571.15. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.75 mL 8.75 mL 17.51 mL
5 mM 0.35 mL 1.75 mL 3.5 mL
10 mM 0.18 mL 0.88 mL 1.75 mL
50 mM 0.04 mL 0.18 mL 0.35 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Krug et al (1973) α,β-Methylene-adenosine 5'-triphosphate. J.Biol.Chem. 248 1203 PMID: 4686923

Burnstock and Kennedy (1985) Is there a basis for distinguishing two types of P2-purinoceptor? Gen.Pharmacol 16 433 PMID: 2996968


If you know of a relevant reference for α,β-Methyleneadenosine 5'-triphosphate trisodium salt, please let us know.

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Keywords: alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt, alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt supplier, P2, agonists, P2-purinoceptor, P2Y, Receptors, Purinergic, P2X, purinoceptors, α, β-Methyleneadenosines, alpha,beta-Methyleneadenosines, 5-triphosphate, trisodium, salt, a,b-Methyleneadenosine, 3209, Tocris Bioscience

1 Citation for α,β-Methyleneadenosine 5'-triphosphate trisodium salt

Citations are publications that use Tocris products. Selected citations for α,β-Methyleneadenosine 5'-triphosphate trisodium salt include:

Haanes and Edvinsson (2014) Expression and characterization of purinergic receptors in rat middle meningeal artery-potential role in migraine. PLoS One 9 e108782 PMID: 25265286


Do you know of a great paper that uses α,β-Methyleneadenosine 5'-triphosphate trisodium salt from Tocris? Please let us know.

Reviews for α,β-Methyleneadenosine 5'-triphosphate trisodium salt

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P2 agonist.
By Anonymous on 05/17/2018
Species: Human

P2X1 and P2X3 agonist, the product works as expected.


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