Potent 20S proteasome inhibitor (IC50 = 0.22 nM). Exhibits cytostatic and cytotoxic effects in tumor cells in vitro.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 475.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.1 mL||10.51 mL||21.02 mL|
|5 mM||0.42 mL||2.1 mL||4.2 mL|
|10 mM||0.21 mL||1.05 mL||2.1 mL|
|50 mM||0.04 mL||0.21 mL||0.42 mL|
References are publications that support the products' biological activity.
Mroczkiewicz et al (2010) Studies of the synthesis of all stereoisomers of MG-132 proteasome inhibitors in the tumor targeting approach. J.Med.Chem. 53 1509 PMID: 20112914
If you know of a relevant reference for (R)-MG 132, please let us know.
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Keywords: (R)-MG 132, supplier, (R)-MG132, 20S, proteasome, inhibitors, inhibits, potent, Proteasome, Proteasome, Tocris Bioscience
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