DBHDA

Pricing Availability   Qty
Cat.No. 6175 - DBHDA | C6H10Br2N2O2 | CAS No. 99584-96-0
Description: Reagent for synthetic biology; converts cysteine to dehydroalanine
Chemical Name: 2,5-Dibromohexanediamide
Datasheet
Citations
Reviews
Literature

Biological Activity

Reagent for synthetic biology; converts cysteine to dehydroalanine (Dha).

Technical Data

M. Wt 301.96
Formula C6H10Br2N2O2
Storage Store at +4°C
CAS Number 99584-96-0
PubChem ID 277410
InChI Key PLSXNAQEJOGNKQ-UHFFFAOYSA-N
Smiles NC(C(CCC(C(N)=O)Br)Br)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.2 100

Preparing Stock Solutions

The following data is based on the product molecular weight 301.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.31 mL 16.56 mL 33.12 mL
5 mM 0.66 mL 3.31 mL 6.62 mL
10 mM 0.33 mL 1.66 mL 3.31 mL
50 mM 0.07 mL 0.33 mL 0.66 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References

References are publications that support the biological activity of the product.

Chalker et al (2011) Methods for converting cysteine to dehydroalanine on peptides and proteins. Chem. Sci. 2 1666

Wright et al (2016) Posttranslational mutagenesis: a chemical strategy for exploring protein side-chain diversity. Science 354 1465 PMID: 27708059

Mulder et al (2016) A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes. Nat.Chem.Biol. 12 523 PMID: 27182664

Lercher et al (2015) Generation of a synthetic GlcNAcylated nucleosome reveals regulation of stability by H2A-Thr101 GlcNAcylation. Nat.Commun. 25 7978 PMID: 26305776


If you know of a relevant reference for DBHDA, please let us know.

View Related Products by Target

Keywords: DBHDA, DBHDA supplier, diacetamide, reagent, synthetic, biology, converts, cysteine, dehydroalanine, Dha, Biochemicals, and, Molecular, Biology, 6175, Tocris Bioscience

Citations for DBHDA

Citations are publications that use Tocris products.

Currently there are no citations for DBHDA. Do you know of a great paper that uses DBHDA from Tocris? Please let us know.

Reviews for DBHDA

There are currently no reviews for this product. Be the first to review DBHDA and earn rewards!

Have you used DBHDA?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


New Product Guide

New Product Guide (Spring/Summer 2018)

Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Aptamers
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells