Broad spectrum glutamate receptor antagonist.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 100 mM in 1eq. NaOH and to 100 mM in water with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 204.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.9 mL||24.49 mL||48.98 mL|
|5 mM||0.98 mL||4.9 mL||9.8 mL|
|10 mM||0.49 mL||2.45 mL||4.9 mL|
|50 mM||0.1 mL||0.49 mL||0.98 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Aksenov et al (2005) Glutamate neurotransmission in the cerebellar interposed nuclei: involvement in classical conditioned eyeblinks and neuronal activity. J.Neurophysiol. 93 44 PMID: 15331619
Jones et al (1984) Structure-activity relations of dipeptide antagonists of excitatory amino acids. Neuroscience 13 573 PMID: 6392929
If you know of a relevant reference for γDGG, please let us know.
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Keywords: Broad spectrum glutamate receptor antagonists Ionotropic Non-Selective iGluR Receptors mGlur Metabotropic γDGG gammaDGG Non-selective Ionotropic Glutamate
2 Citations for γDGG
Citations are publications that use Tocris products. Selected citations for γDGG include:
Chen et al (2013) The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse. J Neurosci 33 8336 PMID: 23658173
Young and Neher (2009) Synaptotagmin has an essential function in synaptic vesicle positioning for synchronous release in addition to its role as a calcium sensor. Neuron 63 482 PMID: 19709630
Do you know of a great paper that uses γDGG from Tocris? If so please let us know.
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