You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
DREADD agonist 21 dihydrochloride
Water soluble version of DREADD agonist 21 (Cat. No. 5548). Potent muscarinic DREADD agonist.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 351.27. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.85 mL||14.23 mL||28.47 mL|
|5 mM||0.57 mL||2.85 mL||5.69 mL|
|10 mM||0.28 mL||1.42 mL||2.85 mL|
|50 mM||0.06 mL||0.28 mL||0.57 mL|
References are publications that support the biological activity of the product.
Chen et al (2015) The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs. ACS Chem.Neurosci. 18 476 PMID: 25587888
If you know of a relevant reference for DREADD agonist 21 dihydrochloride, please let us know.
View Related Products by Target
Keywords: DREADD agonist 21 dihydrochloride, DREADD agonist 21 dihydrochloride supplier, designer, receptors, drugs, DREADDs, hM3Dq, muscarinic, DREADD, ligands, Non-selective, Muscarinics, 6422, Tocris Bioscience
Citations for DREADD agonist 21 dihydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for DREADD agonist 21 dihydrochloride. Do you know of a great paper that uses DREADD agonist 21 dihydrochloride from Tocris? Please let us know.
Reviews for DREADD agonist 21 dihydrochloride
There are currently no reviews for this product. Be the first to review DREADD agonist 21 dihydrochloride and earn rewards!
Have you used DREADD agonist 21 dihydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Chemogenetics Research Bulletin
Produced by Tocris, the chemogenetics research bulletin provides an introduction to chemogenetic methods to manipulate neuronal activity. It outlines the development of RASSLs, DREADDs and PSAMs, and the use of chemogenetic compounds. DREADD ligands and PSEMs available from Tocris are highlighted.
Allosteric GPCR Pharmacology PosterNew
G protein-coupled receptors (GPCRs) are intrinsically allosteric proteins. This poster highlights some of the key insights into allosteric mechanisms of GPCR biology, highlighting key facets of GPCR allostery and therapeutic applications of allosteric modulators.
GPCR Efficacy and Biased Agonism PosterNew
GPCRs can interact with multiple distinct transducers or regulatory proteins and these can be preferentially engaged in an agonist-specific manner giving rise to biased agonism. This poster discusses cutting edge GPCR signaling pharmacology and highlights therapeutic applications of biased agonism.