You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for DMNPE-4 AM-caged-calcium
DMNPE-4 AM-caged-calcium is a calcium cage. In the presence of calcium, the compound will chelate and cage calcium (Kd values are 48 and 19 nM at pH 7.2 and 7.4, respectively; Kd after uncaging = 2 mM). DMNPE-4 AM-caged-calcium is selective for Ca2+ over Mg2+ (Kd = 10 mM). Rapid and efficient calcium release occurs upon photolysis at 350 nm. It can also be used for two-photon uncaging. Extinction coefficient of 5120 M-1 cm-1, quantum yield 0.09. Cell permeable.
Technical Data for DMNPE-4 AM-caged-calcium
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for DMNPE-4 AM-caged-calcium
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for DMNPE-4 AM-caged-calcium
The following data is based on the product molecular weight 849.74. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.18 mL||5.88 mL||11.77 mL|
|5 mM||0.24 mL||1.18 mL||2.35 mL|
|10 mM||0.12 mL||0.59 mL||1.18 mL|
|50 mM||0.02 mL||0.12 mL||0.24 mL|
Product Datasheets for DMNPE-4 AM-caged-calcium
References for DMNPE-4 AM-caged-calcium
References are publications that support the biological activity of the product.
Wang et al (2015) Spontaneous activity of cochlear hair cells triggered by fluid secretion mechanism in adjacent support cells Cell 163 1348 PMID: 26627734
Gordon et al (2008) Brain metabolism dictates the polarity of astrocyte control over arterioles. Nature 456 745 PMID: 18971930
Ellis-Davies et al (2006) Tuning caged calcium: photolabile analogues of EGTA with improved optical and chelation properties. Cell Calcium 39 75 PMID: 16303177
If you know of a relevant reference for DMNPE-4 AM-caged-calcium, please let us know.
View Related Products by Target
Keywords: DMNPE-4 AM-caged-calcium, DMNPE-4 AM-caged-calcium supplier, Caged, calcium, cell, permeable, rapid, photolysis, Second, Messenger, Compounds, Ca2+-Activated, Chloride, Channels, Non-selective, Cav, Potassium, General, Calcium, Signaling, Agents, 5948, Tocris Bioscience
Citations for DMNPE-4 AM-caged-calcium
Citations are publications that use Tocris products.
Currently there are no citations for DMNPE-4 AM-caged-calcium. Do you know of a great paper that uses DMNPE-4 AM-caged-calcium from Tocris? Please let us know.
Reviews for DMNPE-4 AM-caged-calcium
There are currently no reviews for this product. Be the first to review DMNPE-4 AM-caged-calcium and earn rewards!
Have you used DMNPE-4 AM-caged-calcium?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image