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Endogenous kappa receptor agonist.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 0.80 mg/ml in water|
References are publications that support the biological activity of the product.
Dhawan et al (1996) International union of pharmacology XII. Classification of opioid receptors. Pharmacol.Rev. 48 567 PMID: 8981566
Tan-No et al (2008) Cysteine protease inhibitors suppress the development of tolerance to mor. antinociception. Neuropeptides 42 239 PMID: 18440066
If you know of a relevant reference for Dynorphin A, please let us know.
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Keywords: Dynorphin A, Dynorphin A supplier, Endogenous, κ-opioid, kappa-opioid, agonists, KOP, Receptors, OP2, DynorphinA, Kappa, Opioid, 3195, Tocris Bioscience
1 Citation for Dynorphin A
Citations are publications that use Tocris products. Selected citations for Dynorphin A include:
Pina et al (2020) The kappa opioid receptor modulates GABA neuron excitability and synaptic transmission in midbrain-projections from the insular cortex. Neuropharmacology 165 107831 PMID: 31870854
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.