DMNPE-caged ATP diammonium salt

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Cat.No. 5157 - DMNPE-caged ATP diammonium salt | C20H27N6O17P3.2NH3
Description: Caged ATP
Chemical Name: Adenosine 5'-triphosphate P"-[1-(4,5-dimethoxy-2-nitrophenyl)ethyl] ester diammonium salt
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

DMNPE-caged ATP; quantum yield is 0.07. Brain penetrant.

Technical Data

M. Wt 750.44
Formula C20H27N6O17P3.2NH3
Storage Store at -20°C
Purity ≥98% (HPLC)
PubChem ID 90489017
InChI Key HPJJJBGNWXLSNQ-XZDMMRHOSA-N
Smiles N.N.COC1=CC(C(C)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)=C(C=C1OC)[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 75.04 100
DMSO 37.52 50

Preparing Stock Solutions

The following data is based on the product molecular weight 750.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.33 mL 6.66 mL 13.33 mL
5 mM 0.27 mL 1.33 mL 2.67 mL
10 mM 0.13 mL 0.67 mL 1.33 mL
50 mM 0.03 mL 0.13 mL 0.27 mL

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References

References are publications that support the biological activity of the product.

Ellis-Davies (2007) Caged compounds: photorelease technology for control of cellular chemistry and physiology. Nat.Methods 4 619 PMID: 17664946

Jensen et al (2017) Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist. J.Pharmacol.Exp.Ther. 36 441 PMID: 28360333


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Citations for DMNPE-caged ATP diammonium salt

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Literature in this Area

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