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DPTN is a potent and selective A3 adenosine receptor antagonist (Ki values are in the range 0.36 - 1.65 nM (hA3AR) and 1.6 - 8.53 nM (rA3AR)). Reduces intrapulmonary pressure when combined with Dexamethasone (Cat. No. 1126).
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||9.19||20 with gentle warming|
The following data is based on the product molecular weight 459.39. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||10.88 mL||54.42 mL||108.84 mL|
|1 mM||2.18 mL||10.88 mL||21.77 mL|
|2 mM||1.09 mL||5.44 mL||10.88 mL|
|10 mM||0.22 mL||1.09 mL||2.18 mL|
References are publications that support the biological activity of the product.
Gao et al (2021) Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonists. Purinergic Signal. 17 737 PMID: 34713378
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