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Biological Activity for DPTN
DPTN is a potent and selective A3 adenosine receptor antagonist (Ki values are in the range 0.36 - 1.65 nM (hA3AR) and 1.6 - 8.53 nM (rA3AR)). Reduces intrapulmonary pressure when combined with Dexamethasone (Cat. No. 1126).
Technical Data for DPTN
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for DPTN
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||9.19||20 with gentle warming|
Preparing Stock Solutions for DPTN
The following data is based on the product molecular weight 459.39. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||10.88 mL||54.42 mL||108.84 mL|
|1 mM||2.18 mL||10.88 mL||21.77 mL|
|2 mM||1.09 mL||5.44 mL||10.88 mL|
|10 mM||0.22 mL||1.09 mL||2.18 mL|
References for DPTN
References are publications that support the biological activity of the product.
Gao et al (2021) Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonists. Purinergic Signal. 17 737 PMID: 34713378
If you know of a relevant reference for DPTN, please let us know.
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Citations for DPTN
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