You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Dibutyryl-cAMP, sodium salt
Biological Activity for Dibutyryl-cAMP, sodium salt
Dibutyryl-cAMP, sodium salt is a cell-permeable analog of cAMP; activates cAMP-dependent protein kinases. Promotes differentiation of dopaminergic neurons (iDA) from hPSCs in combination with other reagents.
Compound Libraries for Dibutyryl-cAMP, sodium salt
Technical Data for Dibutyryl-cAMP, sodium salt
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Dibutyryl-cAMP, sodium salt
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Dibutyryl-cAMP, sodium salt
The following data is based on the product molecular weight 491.37. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.04 mL||10.18 mL||20.35 mL|
|5 mM||0.41 mL||2.04 mL||4.07 mL|
|10 mM||0.2 mL||1.02 mL||2.04 mL|
|50 mM||0.04 mL||0.2 mL||0.41 mL|
Product Datasheets for Dibutyryl-cAMP, sodium salt
References for Dibutyryl-cAMP, sodium salt
References are publications that support the biological activity of the product.
Carranza et al (1998) Protein kinase A induces recruitment of active Na+,K+-ATPase units to the plasma membrane of rat proximal convoluted tubule cells. J.Physiol. 511 235 PMID: 9679177
Hei et al (1991) Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs Mol.Pharmacol. 39 233 PMID: 1847496
Imamura et al (1998) Differential expression of dystrophin isoforms and utrophin during dibutyryl-cAMP-induced morphological differentiation of rat brain astrocytes. Proc.Natl.Acad.Sci.U.S.A. 95 6139 PMID: 9600931
Xia et al (2016) Transcriptional comparison of human induced and primary midbrain DArgic neurons. Sci.Rep. 6 20270 PMID: 26842779
If you know of a relevant reference for Dibutyryl-cAMP, sodium salt, please let us know.
View Related Products by Target
Keywords: Dibutyryl-cAMP, sodium salt, Dibutyryl-cAMP, sodium salt supplier, Cell-permeable, cAMP, Cyclic, adenosines, Monophosphate, Inositol, Signaling, Signalling, cAMP-dependent, protein, kinase, PKA, Kinase, A, differentiation, ESCs, and, iPSC, Neural, Stem, Cells, 1141, Tocris Bioscience
4 Citations for Dibutyryl-cAMP, sodium salt
Citations are publications that use Tocris products. Selected citations for Dibutyryl-cAMP, sodium salt include:
Telpoukhovskaia et al (2020) Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia. Sci Rep 10
Park et al (2005) Activation of inward rectifier K+ channels by hypoxia in rabbit coronary arterial smooth muscle cells. Am J Physiol Heart Circ Physiol 289 H2461 PMID: 16284107
Kelm et al (2008) The role of protein kinase A in the ethanol-induced increase in spontaneous GABA release onto cerebellar Purkinje neurons. J Neurophysiol 100 3417 PMID: 18945815
Sarkar et al (2018) Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro. Cell Stem Cell 22 684 PMID: 29727680
Do you know of a great paper that uses Dibutyryl-cAMP, sodium salt from Tocris? Please let us know.
Reviews for Dibutyryl-cAMP, sodium salt
There are currently no reviews for this product. Be the first to review Dibutyryl-cAMP, sodium salt and earn rewards!
Have you used Dibutyryl-cAMP, sodium salt?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.