Dibutyryl-cAMP, sodium salt
Cell-permeable analog of cAMP; activates cAMP-dependent protein kinases. Promotes differentiation of dopaminergic neurons (iDA) from hPSCs in combination with other reagents.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 491.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.04 mL||10.18 mL||20.35 mL|
|5 mM||0.41 mL||2.04 mL||4.07 mL|
|10 mM||0.2 mL||1.02 mL||2.04 mL|
|50 mM||0.04 mL||0.2 mL||0.41 mL|
References are publications that support the products' biological activity.
Carranza et al (1998) Protein kinase A induces recruitment of active Na+,K+-ATPase units to the plasma membrane of rat proximal convoluted tubule cells. J.Physiol. 511 235 PMID: 9679177
Hei et al (1991) Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs Mol.Pharmacol. 39 233 PMID: 1847496
Imamura et al (1998) Differential expression of dystrophin isoforms and utrophin during dibutyryl-cAMP-induced morphological differentiation of rat brain astrocytes. Proc.Natl.Acad.Sci.U.S.A. 95 6139 PMID: 9600931
Xia et al (2016) Transcriptional comparison of human induced and primary midbrain dopaminergic neurons. Sci.Rep. 6 20270 PMID: 26842779
If you know of a relevant reference for Dibutyryl-cAMP, sodium salt, please let us know.
View Related Products by Target
Keywords: Dibutyryl-cAMP, sodium salt, supplier, Cell-permeable, cAMP, Cyclic, adenosines, Monophosphate, Inositol, Signaling, Signalling, cAMP-dependent, protein, kinase, PKA, Kinase, A, differentiation, cAMP, ESCs, and, iPSC, Neural, Stem, Cells, cAMP, Tocris Bioscience
1 Citation for Dibutyryl-cAMP, sodium salt
Citations are publications that use Tocris products. Selected citations for Dibutyryl-cAMP, sodium salt include:
Park et al (2005) Activation of inward rectifier K+ channels by hypoxia in rabbit coronary arterial smooth muscle cells. Am J Physiol Heart Circ Physiol 289 H2461 PMID: 16284107
Do you know of a great paper that uses Dibutyryl-cAMP, sodium salt from Tocris? If so please let us know.
Reviews for Dibutyryl-cAMP, sodium salt
There are currently no reviews for this product. Be the first to review Dibutyryl-cAMP, sodium salt and earn rewards!
Have you used Dibutyryl-cAMP, sodium salt?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.