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Description: Caged serine; excited by visible blue light
Chemical Name: O-(4,5-Dimethoxy-2-nitrobenzyl)-L-serine
Purity: ≥98% (HPLC)

Biological Activity for DMNB-caged-Serine

DMNB-caged-Serine is a DMNB-caged serine. Photoactivated to release serine by visible blue light (405 nm) in cells. Incorporated into S.cerevisiae proteins when introduced into growth medium at millimolar concentrations.

Technical Data for DMNB-caged-Serine

M. Wt 300.26
Formula C12H16N2O7
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 780009-55-4
PubChem ID 16741276
Smiles COC1=CC(COC[C@@H](C(O)=O)N)=C([N+]([O-])=O)C=C1OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for DMNB-caged-Serine

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 3 10 with gentle warming

Preparing Stock Solutions for DMNB-caged-Serine

The following data is based on the product molecular weight 300.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.3 mL 166.52 mL 333.04 mL
0.5 mM 6.66 mL 33.3 mL 66.61 mL
1 mM 3.33 mL 16.65 mL 33.3 mL
5 mM 0.67 mL 3.33 mL 6.66 mL

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Product Datasheets for DMNB-caged-Serine

Certificate of Analysis / Product Datasheet
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References for DMNB-caged-Serine

References are publications that support the biological activity of the product.

Lemke et al (2007) Control of protein phosphorylation with a genetically encoded photocaged amino acid. Nat.Chem.Biol. 3 769 PMID: 17965709

If you know of a relevant reference for DMNB-caged-Serine, please let us know.

Keywords: DMNB-caged-Serine, DMNB-caged-Serine supplier, caged, serine, DMNB, photoactivated, photolysis, amino, acids, Caged, Amino, Acid, Compounds, Acids, Unnatural, 6315, Tocris Bioscience

Citations for DMNB-caged-Serine

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