You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for Oxcarbazepine
Oxcarbazepine is an anticonvulsant; protects mice and rats against generalized tonic-clonic seizures induced by electroshock. Thought to act via inhibition of sodium channel activity.
Technical Data for Oxcarbazepine
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Oxcarbazepine
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Oxcarbazepine
The following data is based on the product molecular weight 252.27. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||7.93 mL||39.64 mL||79.28 mL|
|2.5 mM||1.59 mL||7.93 mL||15.86 mL|
|5 mM||0.79 mL||3.96 mL||7.93 mL|
|25 mM||0.16 mL||0.79 mL||1.59 mL|
References for Oxcarbazepine
References are publications that support the biological activity of the product.
Schmutz et al (1994) Oxcarbazepine: preclinical anticonvulsant profile and putative mechanism of action. Epilepsia 35 S47 PMID: 8039471
Ambrosio et al (2002) Mechanism of action of carbamaz. and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024. Neurochem.Res. 27 121 PMID: 11926264
Zheng et al (2009) Oxcarbazepine, not its active metabolite, potentiates GABAA activation and aggravates absence seizures. Epilepsia 50 83 PMID: 18717705
If you know of a relevant reference for Oxcarbazepine, please let us know.
View Related Products by Product Action
Keywords: Oxcarbazepine, Oxcarbazepine supplier, antiepileptics, anticonvulsants, anticonvulsives, sodium, channels, voltage-gated, Na+, voltage-dependent, inhibitors, inhibits, NaV, Voltage-gated, Sodium, Channels, 3864, Tocris Bioscience
Citations for Oxcarbazepine
Citations are publications that use Tocris products.
Currently there are no citations for Oxcarbazepine. Do you know of a great paper that uses Oxcarbazepine from Tocris? Please let us know.
Reviews for Oxcarbazepine
Average Rating: 5 (Based on 1 Review.)
Have you used Oxcarbazepine?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Epilepsy is a brain disease that affects 60 million people globally. More than 20 anti-seizure drugs are currently available, but these do not address the underlying causes of the condition. This poster summarizes current knowledge about the development of the condition and highlights some approaches that have disease-modifying effects in proof-of-concept studies.