Lidocaine

Pricing Availability Delivery Time Qty
Cat.No. 3057 - Lidocaine | C14H22N2O | CAS No. 137-58-6
Description: Na+ channel blocker
Chemical Name: 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Literature

Biological Activity

Anasthetic and class Ib antiarrhythmic agent.  Blocks voltage-gated sodium channels in the inactivated state.

Technical Data

M. Wt 234.34
Formula C14H22N2O
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 137-58-6
PubChem ID 3676
InChI Key NNJVILVZKWQKPM-UHFFFAOYSA-N
Smiles O=C(CN(CC)CC)NC1=C(C)C=CC=C1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 23.43 100

Preparing Stock Solutions

The following data is based on the product molecular weight 234.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.27 mL 21.34 mL 42.67 mL
5 mM 0.85 mL 4.27 mL 8.53 mL
10 mM 0.43 mL 2.13 mL 4.27 mL
50 mM 0.09 mL 0.43 mL 0.85 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Sarraf et al (2003) Tedisamil and lidocaine enhance each other's antiarrhythmic activity against ischaemia-induced arrhythmias in rats. Br.J.Pharmacol. 139 1389 PMID: 12922925


If you know of a relevant reference for Lidocaine, please let us know.

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Keywords: Lidocaine, supplier, Na+, channel, blockers, Sodium, NaV, Channels, voltage-gated, voltage-dependent, Voltage-gated, Sodium, Channels, Voltage-gated, Sodium, Channels, Tocris Bioscience

1 Citation for Lidocaine

Citations are publications that use Tocris products. Selected citations for Lidocaine include:

Miguel Angel Garcia-Bereguiain et al (2016) Spontaneous Release Regulates Synaptic Scaling in the Embryonic Spinal Network In Vivo The Journal of Neuroscience 6 7268 PMID: 27383600


Do you know of a great paper that uses Lidocaine from Tocris? If so please let us know.

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Reviews

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Pathways for Lidocaine

Protocols

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