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L 012 sodium salt
Luminal-based chemiluminescent probe. Detects NAPDH oxidase-derived reactive oxygen and nitrogen species (ROS and RNS). Active in vitro and in vivo.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 310.67. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.22 mL||16.09 mL||32.19 mL|
|5 mM||0.64 mL||3.22 mL||6.44 mL|
|10 mM||0.32 mL||1.61 mL||3.22 mL|
|50 mM||0.06 mL||0.32 mL||0.64 mL|
References are publications that support the biological activity of the product.
Kielland et al (2009) In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic.Biol.Med. 47 760 PMID: 19539751
Zhou et al (2012) Noninvasive assessment of localized inflammatory responses. Free Radic.Biol.Med. 52 218 PMID: 22080048
Ichibangase et al (2013) Evaluation of lophine derivatives as L-012 (luminol analog)-dependent chemiluminescence enhancers for measuring horseradish peroxidase and H2 O2. Luminescence. 29 118 PMID: 23630098
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