Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewLatrunculin B is an inhibitor of actin polymerization. Interacts with G-actin in a 1:1 ratio to inhibit polymerization into F-actin in vitro (IC50 values are ~60 and ~900 nM in absence and presence of calf serum, respectively). Marine toxin.
M. Wt | 395.51 |
Formula | C20H29NO5S |
Storage | Store at -20°C |
Purity | ≥95% (HPLC) |
CAS Number | 76343-94-7 |
PubChem ID | 3892 |
InChI Key | NSHPHXHGRHSMIK-UHFFFAOYSA-N |
Smiles | O=C1/C=C(C)\CC/C=C\[C@@H](C)CC[C@@H]2C[C@H](C[C@](O)([C@@]3([H])NC(SC3)=O)O2)O1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMSO | 19.78 | 50 | |
ethanol | 19.78 | 50 |
The following data is based on the product molecular weight 395.51. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.5 mM | 5.06 mL | 25.28 mL | 50.57 mL |
2.5 mM | 1.01 mL | 5.06 mL | 10.11 mL |
5 mM | 0.51 mL | 2.53 mL | 5.06 mL |
25 mM | 0.1 mL | 0.51 mL | 1.01 mL |
References are publications that support the biological activity of the product.
Wakatsuki et al (2001) Effects of cytochalasin D and latrunculin B on mechanical properties of cells. J.Cell.Sci. 114 1025 PMID: 11181185
If you know of a relevant reference for Latrunculin B, please let us know.
Keywords: Latrunculin B, Latrunculin B supplier, Inhibitors, Inhibits, Actin, filament, modulator, G-Actin, F-Actin, monomers, polymers, toxin, 3974, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for Latrunculin B. Do you know of a great paper that uses Latrunculin B from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review Latrunculin B and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image