RepSox

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Cat.No. TB3742-RMU - RepSox | C17H13N5 | CAS No. 446859-33-2
Description: RepSox synthesized to Ancillary Material Grade
Alternative Names: ALK5 Inhibitor II, SJN 2511, E-616452
Chemical Name: 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
Purity: ≥99%
Datasheet
Citations
Reviews
Literature (4)

Biological Activity for RepSox

RepSox is an ancillary Material Grade version of product RepSox (Cat. No. 3742). Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.

Find out more about our Ancillary Material Grade product range.

Technical Data for RepSox

M. Wt 287.32
Formula C17H13N5
Storage Store at 2-8°C
Purity ≥99%
CAS Number 446859-33-2
InChI Key LBPKYPYHDKKRFS-UHFFFAOYSA-N
Smiles CC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for RepSox

Certificate of Analysis is currently unavailable on-line.
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References for RepSox

References are publications that support the biological activity of the product.

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Keywords: RepSox, RepSox supplier, Ancillary, Material, Grade, potent, inhibitors, inhibits, TGF-betaRI, TGF-beta, TGFbRI, TGFbR1, tgf-b1, ALK5, Transforming,Growth, Factors, Beta, stem, cells, E-616452, SJN2511, SJN, 2511, Stem, Cell, Reprogramming, manufacturing, gene, cell, therapies, GMP, Inhibitor, II, Small, Molecules, TB3742-RMU, Tocris Bioscience

Citations for RepSox

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Reviews for RepSox

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Stem Cell

Stem Cell Research Product Guide

This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:

  • Self-renewal and Maintenance
  • Differentiation
  • Reprogramming
  • Organoid Generation
  • GMP and Ancillary Material Grade Products
Stem Cells

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cell Workflow

Stem Cell Workflow Poster

Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.

Stem Cells

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.