Pricing Availability   Qty
Description: RepSox synthesized to Ancillary Material Grade
Alternative Names: ALK5 Inhibitor II, SJN 2511, E-616452
Chemical Name: 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
Purity: ≥99%
Citations (1)
Literature (4)

Biological Activity for RepSox

RepSox is an ancillary Material Grade version of product RepSox (Cat. No. 3742). Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.

Find out more about our Ancillary Material Grade product range.

Technical Data for RepSox

M. Wt 287.32
Formula C17H13N5
Storage Store at 2-8°C
Purity ≥99%
CAS Number 446859-33-2
Smiles CC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for RepSox

Certificate of Analysis is currently unavailable on-line.
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References for RepSox

References are publications that support the biological activity of the product.

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Keywords: RepSox, RepSox supplier, Ancillary, Material, Grade, potent, inhibitors, inhibits, TGF-betaRI, TGF-beta, TGFbRI, TGFbR1, tgf-b1, ALK5, Transforming,Growth, Factors, Beta, stem, cells, E-616452, SJN2511, SJN, 2511, Stem, Cell, Reprogramming, manufacturing, gene, cell, therapies, GMP, Inhibitor, II, Small, Molecules, TB3742-RMU, Tocris Bioscience

1 Citation for RepSox

Citations are publications that use Tocris products. Selected citations for RepSox include:

Mishra et al (2022) Improved loss-of-function CRISPR-Cas9 genome editing in human cells concomitant with inhibition of TGF-beta signaling. Mol.Ther.Nucleic Acids 28 202 PMID: 35402072

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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Stem Cell Research Product Guide

Stem Cell Research Product Guide

This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:

  • Self-renewal and Maintenance
  • Differentiation
  • Reprogramming
  • Organoid Generation
  • GMP and Ancillary Material Grade Products
Stem Cells Scientific Review

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cell Workflow Poster

Stem Cell Workflow Poster

Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.

Stem Cells Poster

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.