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Biological Activity for Rucaparib camsylate
Sold for research purposes under agreement from Pfizer Inc.
Compound Libraries for Rucaparib camsylate
Technical Data for Rucaparib camsylate
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Rucaparib camsylate
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Rucaparib camsylate
The following data is based on the product molecular weight 555.66. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.8 mL||9 mL||18 mL|
|5 mM||0.36 mL||1.8 mL||3.6 mL|
|10 mM||0.18 mL||0.9 mL||1.8 mL|
|50 mM||0.04 mL||0.18 mL||0.36 mL|
Product Datasheets for Rucaparib camsylate
References for Rucaparib camsylate
References are publications that support the biological activity of the product.
Thomas et al (2007) Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial. Mol.Cancer Ther. 6 945 PMID: 17363489
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Keywords: Rucaparib camsylate, Rucaparib camsylate supplier, PARP, inhibitors, inhibits, Poly(ADP-ribose), Polymerase, chemosentizers, chemosensitizes, CO-338, 6230, Tocris Bioscience
Citations for Rucaparib camsylate
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Literature in this Area
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Cell Cycle & DNA Damage Repair Poster
In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. Adapted from the 2015 Cancer Product Guide, Edition 3, this poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.