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Submit ReviewRemodelin
Description: N-acetyltransferase 10 (NAT10) inhibitor
Chemical Name: 4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile
Purity: ≥99% (HPLC)
Biological Activity for Remodelin
Remodelin is a N-acetyltransferase 10 (NAT10) inhibitor. Improves nuclear shape in HGPS (Hutchinson-Gilford progeria syndrome) cells and lamin A/C depleted cells.
Technical Data for Remodelin
| M. Wt | 282.36 |
| Formula | C15H14N4S |
| Storage | Store at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 949912-58-7 |
| PubChem ID | 44442376 |
| InChI Key | XAEJIFARBQJLML-UHFFFAOYSA-N |
| Smiles | N#CC(C=C1)=CC=C1C2=CSC(N/N=C3CCCC/3)=N2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Remodelin
References for Remodelin
References are publications that support the biological activity of the product.
Larrieu et al (2014) Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science 344 527 PMID: 24786082
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Keywords: Remodelin, Remodelin supplier, NAT10, N-acetyltransferase, 10, aging, inhibitors, HGPS, Hutchinson-Gilford, progeria, syndrome, laminopathies, laminopathy, inhibits, Other, Transferases, 5193, Tocris Bioscience
Citations for Remodelin
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Currently there are no citations for Remodelin.
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