You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
HIV-1 and HIV-2 protease inhibitor (EC50 values are 0.022-0.13 and 0.16 μM, respectively). Blocks the metabolism of protease inhibitors by liver enzyme cytochrome P450-3A4 (CYP3A4). Orally bioavailable.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||14.42||20 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 720.94. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||6.94 mL||34.68 mL||69.35 mL|
|1 mM||1.39 mL||6.94 mL||13.87 mL|
|2 mM||0.69 mL||3.47 mL||6.94 mL|
|10 mM||0.14 mL||0.69 mL||1.39 mL|
References are publications that support the biological activity of the product.
Kempf et al (1995) ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans. Proc.Natl.Acad.Sci.U.S.A. 92 2484 PMID: 7708670
Kempf et al (1998) Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy. J.Med.Chem. 41 602 PMID: 9484509
Zeldin et al (2004) Pharmacological and therapeutic properties of ritonavir-boosted protease inhibitor therapy in HIV-infected patients. J.Antimicrob.Chemother. 53 4 PMID: 14657084
If you know of a relevant reference for Ritonavir, please let us know.
View Related Products by Product Action
Keywords: Ritonavir, Ritonavir supplier, HIV-1, HIV-2, proteases, inhibitors, inhibits, cytochrome, P450-3A4, human, immunodeficiency, virus, orally, active, ABT-538, A-84538, Abbot, 84538, Other, Proteases, Antivirals, 5856, Tocris Bioscience
Citations for Ritonavir
Citations are publications that use Tocris products.
Currently there are no citations for Ritonavir. Do you know of a great paper that uses Ritonavir from Tocris? Please let us know.
Reviews for Ritonavir
There are currently no reviews for this product. Be the first to review Ritonavir and earn rewards!
Have you used Ritonavir?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide [Spring/Summer 2019]
Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells