Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
RIPK2 inhibitor 1 is a potent receptor-interacting protein kinase 2 (RIPK2) inhibitor (IC50 of 5-10 nM). It inhibits NF-κB activity and decreases cancer cell proliferation by 70%. In vivo, RIPK2 inhibitor 1 inhibits intestinal and lung inflammation with low toxicity in rodent models.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 410.48. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.44 mL||12.18 mL||24.36 mL|
|5 mM||0.49 mL||2.44 mL||4.87 mL|
|10 mM||0.24 mL||1.22 mL||2.44 mL|
|50 mM||0.05 mL||0.24 mL||0.49 mL|
References are publications that support the biological activity of the product.
Salla et al (2018) Identification and characterization of novel receptor-interacting serine/threonine-protein kinase 2 inhibitors using structural similarity analysis. J.Pharmacol.Exp.Ther. 365 354 PMID: 29555876
If you know of a relevant reference for RIPK2 inhibitor 1, please let us know.
Keywords: RIPK2 inhibitor 1, RIPK2 inhibitor 1 supplier, TCMS1, anti, inflammatory, RIPK2, RIPK, RIP, kinase, inhibitors, inhibits, receptor-interacting, protein, 2, potent, in, vivo, Kinases, 6603, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for RIPK2 inhibitor 1. Do you know of a great paper that uses RIPK2 inhibitor 1 from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review RIPK2 inhibitor 1 and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image