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RU 24969 hemisuccinate is a potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 287.34. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||6.96 mL||34.8 mL||69.6 mL|
|2.5 mM||1.39 mL||6.96 mL||13.92 mL|
|5 mM||0.7 mL||3.48 mL||6.96 mL|
|25 mM||0.14 mL||0.7 mL||1.39 mL|
References are publications that support the biological activity of the product.
Gudermann et al (1993) Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 43 412 PMID: 8450834
Tomkins and O'Neill (2000) Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129 PMID: 10837852
Guillaume et al (1987) Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antiDArgic properties. Eur.J.Med.Chem. 22 33
If you know of a relevant reference for RU 24969 hemisuccinate, please let us know.
Keywords: RU 24969 hemisuccinate, RU 24969 hemisuccinate supplier, 5-HT1B/1A, agonists, Serotonin, Receptors, RU24969, hemisuccinate, C14H16N2O.0.5C4H6O4, 5-HT1A, 0912, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for RU 24969 hemisuccinate include:
Lawson et al (2016) Effects of oxyt. on Serotonin 1B Agonist-induced Autism-like Behavior in Mice Behavioural Brain Research 314 52 PMID: 27439030
Do you know of a great paper that uses RU 24969 hemisuccinate from Tocris? Please let us know.
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Drug treatment 0 or 10 mg/kg RU24969
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
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