You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
RN 9893 hydrochloride
Biological Activity for RN 9893 hydrochloride
RN 9893 hydrochloride is a potent and selective TRPV4 antagonist (IC50 values are 320, 420 and 660 nM for mouse, human and rat channels, respectively). Exhibits >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets. Orally bioavailable.
Compound Libraries for RN 9893 hydrochloride
Technical Data for RN 9893 hydrochloride
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for RN 9893 hydrochloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for RN 9893 hydrochloride
The following data is based on the product molecular weight 536.95. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.86 mL||9.31 mL||18.62 mL|
|5 mM||0.37 mL||1.86 mL||3.72 mL|
|10 mM||0.19 mL||0.93 mL||1.86 mL|
|50 mM||0.04 mL||0.19 mL||0.37 mL|
Product Datasheets for RN 9893 hydrochloride
References for RN 9893 hydrochloride
References are publications that support the biological activity of the product.
Wei et al (2015) Identification of orally-bioavailable antagonists of the TRPV4 ion-channel. Bioorg.Med.Chem.Lett. 25 4011 PMID: 26235950
If you know of a relevant reference for RN 9893 hydrochloride, please let us know.
View Related Products by Product Action
Keywords: RN 9893 hydrochloride, RN 9893 hydrochloride supplier, RN9893, hydrochloride, potent, selective, TRPV4, transient, receptors, potential, channels, orally, bioavailable, 1803003-68-0, TRPV, 5678, Tocris Bioscience
Citations for RN 9893 hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for RN 9893 hydrochloride. Do you know of a great paper that uses RN 9893 hydrochloride from Tocris? Please let us know.
Reviews for RN 9893 hydrochloride
There are currently no reviews for this product. Be the first to review RN 9893 hydrochloride and earn rewards!
Have you used RN 9893 hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image