Endogenous estrogen receptor (ER) agonist (Ki values are 0.12 and 0.13 nM for ERα and ERβ respectively). Also high affinity ligand at membrane estrogen GPR30 receptors.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 272.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.67 mL||18.36 mL||36.71 mL|
|5 mM||0.73 mL||3.67 mL||7.34 mL|
|10 mM||0.37 mL||1.84 mL||3.67 mL|
|50 mM||0.07 mL||0.37 mL||0.73 mL|
References are publications that support the biological activity of the product.
Kuiper et al (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 138 863 PMID: 9048584
Thomas et al (2005) Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146 624 PMID: 15539556
If you know of a relevant reference for β-Estradiol, please let us know.
View Related Products by Product Action
Keywords: beta-Estradiol, beta-Estradiol supplier, Endogenous, ER, agonists, Estrogen, Receptors, GPR30, beta-Estradiol, b-estradiol, β-estradiol, 17, β-Estradiol, beta-estradiol, GPER, 17b-Estradiol, and, Related, (GPER), 2824, Tocris Bioscience
2 Citations for β-Estradiol
Citations are publications that use Tocris products. Selected citations for β-Estradiol include:
Al-Khyatt (2018) Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro. BMC Cancer 18 121 PMID: 29390981
Leal et al (2012) p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF. PLoS One 7 e49817 PMID: 23239970
Do you know of a great paper that uses β-Estradiol from Tocris? Please let us know.
Reviews for β-Estradiol
There are currently no reviews for this product. Be the first to review β-Estradiol and earn rewards!
Have you used β-Estradiol?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.