You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for Etifoxine hydrochloride
Etifoxine hydrochloride is a potentiator of GABAA receptor function in cultured neurons. Preferentially acts on β2 or β3 subunit-containing GABAA receptors. Exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration.
Compound Libraries for Etifoxine hydrochloride
Technical Data for Etifoxine hydrochloride
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Etifoxine hydrochloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|water||1.69||5 with gentle warming|
Preparing Stock Solutions for Etifoxine hydrochloride
The following data is based on the product molecular weight 337.24. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.97 mL||14.83 mL||29.65 mL|
|5 mM||0.59 mL||2.97 mL||5.93 mL|
|10 mM||0.3 mL||1.48 mL||2.97 mL|
|50 mM||0.06 mL||0.3 mL||0.59 mL|
Product Datasheets for Etifoxine hydrochloride
References for Etifoxine hydrochloride
References are publications that support the biological activity of the product.
Hamon et al (2003) The modulatory effects of the anxiolytic etifoxine on GABAA receptors are mediated by the β subunit. Neuropharmacology 45 293 PMID: 12871647
Girard et al (2008) Etifoxine improves peripheral nerve regeneration and functional recovery. Proc.Natl.Acad.Sci. 105 20505
If you know of a relevant reference for Etifoxine hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Etifoxine hydrochloride, Etifoxine hydrochloride supplier, Etifoxine, HCl, potentiates, GABAA, receptor, potentiator, anxiolytic, anxiety, drug, translocator, protein, ligand, TSPO, anticonvulsants, Receptors, Neuronal, Metabolism, Translocator, Protein, 3113, Tocris Bioscience
Citations for Etifoxine hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for Etifoxine hydrochloride. Do you know of a great paper that uses Etifoxine hydrochloride from Tocris? Please let us know.
Reviews for Etifoxine hydrochloride
There are currently no reviews for this product. Be the first to review Etifoxine hydrochloride and earn rewards!
Have you used Etifoxine hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.