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Biological Activity for 5-Ethynyluridine
5-Ethynyluridine is a cell-permeable uridine analog. 5-Ethynyluridine can be used in vitro and in vivo to label newly synthesized RNA. 5-Ethynyluridine can be used to study changes in transcription.
Technical Data for 5-Ethynyluridine
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for 5-Ethynyluridine
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for 5-Ethynyluridine
The following data is based on the product molecular weight 268.23. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.73 mL||18.64 mL||37.28 mL|
|5 mM||0.75 mL||3.73 mL||7.46 mL|
|10 mM||0.37 mL||1.86 mL||3.73 mL|
|50 mM||0.07 mL||0.37 mL||0.75 mL|
Product Datasheets for 5-Ethynyluridine
References for 5-Ethynyluridine
References are publications that support the biological activity of the product.
Nainar et al (2020) An optimized chemical-genetic method for cell-specific metabolic labeling of RNA. Nat.Methods 17 311 PMID: 32015544
Van't Sant et al (2021) In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration. Acta Neuropathol.Commun. 9 94 PMID: 34020718
If you know of a relevant reference for 5-Ethynyluridine, please let us know.
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Citations for 5-Ethynyluridine
Citations are publications that use Tocris products.
Currently there are no citations for 5-Ethynyluridine. Do you know of a great paper that uses 5-Ethynyluridine from Tocris? Please let us know.
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Literature in this Area
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