(R)-(+)-Etomoxir sodium salt

Pricing Availability Delivery Time Qty
Cat.No. 4539 - (R)-(+)-Etomoxir sodium salt | C15H18ClNaO4 | CAS No. 828934-41-4
Description: Carnitine palmitoyltransferase I (CPT1) inhibitor
Chemical Name: (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt
Purity: ≥98% (HPLC)

Biological Activity

Inhibitor of carnitine palmitoyltransferase I (CPT1); inhibits β-oxidation in mitochondria. Shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells.

Technical Data

M. Wt 320.74
Formula C15H18ClNaO4
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 828934-41-4
PubChem ID 57345784
Smiles [Na+].[O-]C(=O)[C@@]1(CCCCCCOC2=CC=C(Cl)C=C2)CO1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 6.41 20mM with gentle warming
ethanol 6.41 20
water 6.41 20

Preparing Stock Solutions

The following data is based on the product molecular weight 320.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.12 mL 15.59 mL 31.18 mL
5 mM 0.62 mL 3.12 mL 6.24 mL
10 mM 0.31 mL 1.56 mL 3.12 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet


References are publications that support the products' biological activity.

Xu et al (2003) Etomoxir mediates differential metabolic channeling of fatty acid and glycerol precursors into cardiolipin in H9c2 cells. J.Lipid Res. 44 415 PMID: 12576524

Agius et al (1991) Stereospecificity of the inhibition of etomoxir of fatty acid and cholesterol synthesis in isolated rat hepatocytes. Biochem.Pharmacol. 42 1717 PMID: 1930298

Rupp et al (1992) Modification of subcellular organelles in pressure-overloaded heart by etomoxir, a carnitine palmitoyltransferase I inhibitor. FASEB J. 6 2349 PMID: 1531968

If you know of a relevant reference for (R)-(+)-Etomoxir sodium salt, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Other Transferase Inhibitors

Keywords: (R)-(+)-Etomoxir sodium salt, supplier, carnitine, o-palmitoyltransferase, acyltransferases, I, CPT1, inhibitors, inhibits, Other, Transferases, Other, Transferases, Tocris Bioscience

Citations for (R)-(+)-Etomoxir sodium salt

Citations are publications that use Tocris products.

Currently there are no citations for (R)-(+)-Etomoxir sodium salt. Do you know of a great paper that uses (R)-(+)-Etomoxir sodium salt from Tocris? If so please let us know.

Commented out for usability testing


TODO: Add Reviews

Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for (R)-(+)-Etomoxir sodium salt


TODO: Add Protocols