(R)-(+)-Etomoxir sodium salt
Inhibitor of carnitine palmitoyltransferase I (CPT1); inhibits β-oxidation in mitochondria. Shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||6.41||20 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 320.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||15.59 mL||77.94 mL||155.89 mL|
|1 mM||3.12 mL||15.59 mL||31.18 mL|
|2 mM||1.56 mL||7.79 mL||15.59 mL|
|10 mM||0.31 mL||1.56 mL||3.12 mL|
References are publications that support the biological activity of the product.
Xu et al (2003) Etomoxir mediates differential metabolic channeling of fatty acid and glycerol precursors into cardiolipin in H9c2 cells. J.Lipid Res. 44 415 PMID: 12576524
Agius et al (1991) Stereospecificity of the inhibition of etomoxir of fatty acid and cholesterol synthesis in isolated rat hepatocytes. Biochem.Pharmacol. 42 1717 PMID: 1930298
Rupp et al (1992) Modification of subcellular organelles in pressure-overloaded heart by etomoxir, a carnitine palmitoyltransferase I inhibitor. FASEB J. 6 2349 PMID: 1531968
If you know of a relevant reference for (R)-(+)-Etomoxir sodium salt, please let us know.
View Related Products by Product Action
Keywords: (R)-(+)-Etomoxir sodium salt, (R)-(+)-Etomoxir sodium salt supplier, carnitine, o-palmitoyltransferase, acyltransferases, I, CPT1, inhibitors, inhibits, Other, Transferases, 4539, Tocris Bioscience
Citations for (R)-(+)-Etomoxir sodium salt
Citations are publications that use Tocris products.
Currently there are no citations for (R)-(+)-Etomoxir sodium salt. Do you know of a great paper that uses (R)-(+)-Etomoxir sodium salt from Tocris? Please let us know.
Reviews for (R)-(+)-Etomoxir sodium salt
Average Rating: 5 (Based on 2 Reviews.)
Have you used (R)-(+)-Etomoxir sodium salt?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Etomoxir was used as a CPT1 inhibitor in endothelial cells. The data was shown in the publication PubMed ID 29429925.
Exogenous application on acute brain slices
Pre-incubation of 15 minutes at 100 uM
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Fall/Winter 2018/2019)New
Our new product guide highlights over 190 new products added to the Tocris Bioscience range during the second half of 2018.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells