Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Epoprostenol is an endogenous prostanoid that is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.
|Storage||Desiccate at -80°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 374.45. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.67 mL||13.35 mL||26.71 mL|
|5 mM||0.53 mL||2.67 mL||5.34 mL|
|10 mM||0.27 mL||1.34 mL||2.67 mL|
|50 mM||0.05 mL||0.27 mL||0.53 mL|
References are publications that support the biological activity of the product.
Kobzar et al (2001) Comparison of anti-aggregatory effects of PGI2, PGI3 and ilo. on human and rabbit platelets. Cell.Physiol.Biochem. 11 279 PMID: 11684817
Oliva and Nicosia (1987) PGI2-receptors and molecular mechanisms in platelets and vasculature: state of the art. Pharmacol.Res.Comm. 19 735
If you know of a relevant reference for Epoprostenol, please let us know.
Keywords: Epoprostenol, Epoprostenol supplier, Endogenous, IP, receptors, agonists, Prostanoid, prostaglandins, prostacyclins, eicosanoids, Prostaglandin, I2, Prostacyclin, Receptors, 2989, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for Epoprostenol include:
Barwari et al (2018) Inhibition of profibrotic microRNA-21 affects platelets and their releasate. JCI Insight 3 PMID: 30385722
Armstrong et al (2015) Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction. Blood 126 e11 PMID: 26215112
Do you know of a great paper that uses Epoprostenol from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review Epoprostenol and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.