cis VH 032, amine dihydrochloride

Pricing Availability   Qty
Cat.No. 6969 - cis VH 032, amine dihydrochloride | C22H30N4O3S.2HCl | CAS No. 2376990-32-6
Description: Negative control for VH 032, amine (Cat. No. 6462)
Chemical Name: (2S,4S)-1-[(2S)-2-Amino-3,3-dimethyl-butanoyl]-4-hydroxy-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide dihydrochloride
Purity: ≥98% (HPLC)
Citations (1)
Literature (1)

Biological Activity

Negative control for the functionalized VHL ligand VH 032, amine (Cat. No. 6462).

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M. Wt 503.48
Formula C22H30N4O3S.2HCl
Storage Desiccate at RT
Purity ≥98% (HPLC)
CAS Number 2376990-32-6
Smiles CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@@H](CN3C([C@H](C(C)(C)C)N)=O)O)=O)SC=N1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.


References are publications that support the biological activity of the product.

If you know of a relevant reference for cis VH 032, amine dihydrochloride, please let us know.

Keywords: cis VH 032, amine dihydrochloride, cis VH 032, amine dihydrochloride supplier, VH032, amine, 2HCl, protein, degrader, 1, VHL, VL, 269, PROTACs, E3, ligase, ligands, negative, control, 2115897-23-7, 1797406-78-0, Functionalized, Ligase, Ligands, 6969, Tocris Bioscience

1 Citation for cis VH 032, amine dihydrochloride

Citations are publications that use Tocris products. Selected citations for cis VH 032, amine dihydrochloride include:

Smalley et al (2020) PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes. Chem.Commun.(Camb) 56 4476 PMID: 32201871

Do you know of a great paper that uses cis VH 032, amine dihydrochloride from Tocris? Please let us know.

Reviews for cis VH 032, amine dihydrochloride

There are currently no reviews for this product. Be the first to review cis VH 032, amine dihydrochloride and earn rewards!

Have you used cis VH 032, amine dihydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Targeted Protein Degradation

Targeted Protein Degradation Poster

Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia