CNV Dopamine

Pricing Availability   Qty
Cat.No. 6354 - CNV Dopamine | C18H20N2O8
Description: Caged dopamine; photolysed by UV light
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (4)

Biological Activity

Carboxynitroveratryl (CNV)-caged dopamine (Cat. No. 3548); releases dopamine upon ultraviolet light stimulation (365 nm). Induces dopaminergic currents upon photolysis in brain slices expressing wild-type or GFP-labeled D2 receptors. Displays no decrease in current (rundown) with UV light flash duration of up to 100 ms. Pharmacologically inactive prior to photolysis.

Technical Data

M. Wt 392.36
Formula C18H20N2O8
Storage Store at -20°C
Purity ≥98% (HPLC)
InChI Key TZSFDUOAUWDBIB-UHFFFAOYSA-N
Smiles OC1=CC(CCN)=CC=C1OC(C(O)=O)C2=CC(OC)=C(OC)C=C2[N+]([O-])=O.NCCC3=CC=C(O)C(OC(C(O)=O)C4=CC(OC)=C(OC)C=C4[N+]([O-])=O)=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.24 100
water 19.62 50

Preparing Stock Solutions

The following data is based on the product molecular weight 392.36. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.55 mL 12.74 mL 25.49 mL
5 mM 0.51 mL 2.55 mL 5.1 mL
10 mM 0.25 mL 1.27 mL 2.55 mL
50 mM 0.05 mL 0.25 mL 0.51 mL

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References

References are publications that support the biological activity of the product.

Robinson et al (2017) Desensitized D2 autoreceptors are resistant to trafficking. Sci.Rep. 7 4379 PMID: 28663556


If you know of a relevant reference for CNV Dopamine, please let us know.

Keywords: CNV Dopamine, CNV Dopamine supplier, caged, dopamine, agonists, receptor, Carboxynitroveratryl, CNV, photolysis, Caged, Dopamine, Compounds, Non-selective, 6354, Tocris Bioscience

Citations for CNV Dopamine

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Currently there are no citations for CNV Dopamine. Do you know of a great paper that uses CNV Dopamine from Tocris? Please let us know.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Neurodegeneration

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