Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
CU CPT 9a is a potent TLR8 inhibitor (IC50 = 0.5 nM and Kd = 21 nM). Stabilizes the TLR8 dimer in its resting state, preventing activation. Suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.
Sold under license from the University of Colorado
CU CPT 9a is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Antiviral Library. Find out more about compound libraries available from Tocris.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 265.31. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.77 mL||18.85 mL||37.69 mL|
|5 mM||0.75 mL||3.77 mL||7.54 mL|
|10 mM||0.38 mL||1.88 mL||3.77 mL|
|50 mM||0.08 mL||0.38 mL||0.75 mL|
References are publications that support the biological activity of the product.
Zhang et al (2018) Small-molecule inhibition of TLR8 through stabilization of its resting state. Nat.Chem.Biol. 14 58 PMID: 29155428
If you know of a relevant reference for CU CPT 9a, please let us know.
Keywords: CU CPT 9a, CU CPT 9a supplier, CUCPT9a, toll-like, receptors, TLR8, inhibitors,, inhibits, potent, Toll-like, Receptors, 6479, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for CU CPT 9a. Do you know of a great paper that uses CU CPT 9a from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review CU CPT 9a and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.