You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for GPBAR-A
GPBAR-A is a gPBA receptor agonist. Upregulates GLP-1 secretion from intestinal cultures. Increases MQAE-fluorescence suggesting a decrease in intracellular chloride concentration in gallbladder epithelial cells.
Compound Libraries for GPBAR-A
Technical Data for GPBAR-A
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for GPBAR-A
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for GPBAR-A
The following data is based on the product molecular weight 484.37. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.06 mL||10.32 mL||20.65 mL|
|5 mM||0.41 mL||2.06 mL||4.13 mL|
|10 mM||0.21 mL||1.03 mL||2.06 mL|
|50 mM||0.04 mL||0.21 mL||0.41 mL|
References for GPBAR-A
References are publications that support the biological activity of the product.
Parker et al (2012) Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion. Br.J.Pharmacol. 165 414 PMID: 21718300
Keitel et al (2009) The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders. Hepatology 50 861 PMID: 19582812
If you know of a relevant reference for GPBAR-A, please let us know.
View Related Products by Product Action
Keywords: GPBAR-A, GPBAR-A supplier, TGR5, agonists, g-protein, bile, acid, receptors, GPBA, GPBAR, Receptors, 4478, Tocris Bioscience
1 Citation for GPBAR-A
Citations are publications that use Tocris products. Selected citations for GPBAR-A include:
Kowal et al (2015) Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells. Stem Cells Transl Med 13 28 PMID: 26050734
Do you know of a great paper that uses GPBAR-A from Tocris? Please let us know.
Reviews for GPBAR-A
There are currently no reviews for this product. Be the first to review GPBAR-A and earn rewards!
Have you used GPBAR-A?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.