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Sphingosine-1-phosphate receptor 1 (S1P1) and 5 (S1P5) agonist.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 440.88. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.27 mL||11.34 mL||22.68 mL|
|5 mM||0.45 mL||2.27 mL||4.54 mL|
|10 mM||0.23 mL||1.13 mL||2.27 mL|
|50 mM||0.05 mL||0.23 mL||0.45 mL|
References are publications that support the biological activity of the product.
Bigaud et al (2014) Second generation S1P pathway modulators: research strategies and clinical developments. Biochim.Biophys.Acta. 1841 745 PMID: 24239768
Subei and Cohen (2015) Sphingosine 1-phosphate receptor modulators in multiple sclerosis. CNS.Drugs. 29 565 PMID: 26239599
If you know of a relevant reference for GSK 2018682, please let us know.
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