You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for BETP
BETP is a selective positive allosteric modulator and partial agonist of the glucagon-like peptide 1 (GLP-1) receptor. Increases binding affinity of oxyntomodulin for the GLP-1 receptor. Potentiates oxyntomodulin-mediated GLP-1 receptor signaling in vitro and insulin secretion in vivo. Has no effect on GLP-2, GIP, PTH or glucagon receptors.
Compound Libraries for BETP
Technical Data for BETP
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for BETP
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for BETP
The following data is based on the product molecular weight 406.42. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.46 mL||12.3 mL||24.61 mL|
|5 mM||0.49 mL||2.46 mL||4.92 mL|
|10 mM||0.25 mL||1.23 mL||2.46 mL|
|50 mM||0.05 mL||0.25 mL||0.49 mL|
References for BETP
References are publications that support the biological activity of the product.
Willard et al (2012) Small molecule allosteric modulation of the glucagon-like Peptide-1 receptor enhances the Insotropic effect of oxyntomodulin. Mol.Pharmacol. 82 1066 PMID: 22930710
Sloop et al (2010) Novel small molecule glucagon-like peptide-1 receptor agonist stimulates Ins secretion in rodents and from human islets. Diabetes 59 3099 PMID: 20823098
Cheong et al (2012) Two small molecule agonists of glucagon-like peptide-1 receptor modulate the receptor activation response differently. Biochem.Biophys.Res.Comm. 417 558 PMID: 22177947
If you know of a relevant reference for BETP, please let us know.
View Related Products by Product Action
Keywords: BETP, BETP supplier, Allosteric, modulators, GLP-1, GLP1, receptors, glucagon-like, peptide, agonists, PAM, Glucagon-Like, Peptide, 1, Receptors, 4778, Tocris Bioscience
Citations for BETP
Citations are publications that use Tocris products.
Currently there are no citations for BETP. Do you know of a great paper that uses BETP from Tocris? Please let us know.
Reviews for BETP
There are currently no reviews for this product. Be the first to review BETP and earn rewards!
Have you used BETP?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.