You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Inhibitor of human lactate dehydrogenase (LDH) (Ki values are 5.46 and 15.1 μM for LDH-A and LDH-B, respectively, in competition with pyruvate). Inhibits lactate production and decreases ATP synthesis in PLD/PRF/5 cells; thought to decrease cell viability via impairment of aerobic glycolysis.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 316.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.05 mM||63.24 mL||316.2 mL||632.39 mL|
|0.25 mM||12.65 mL||63.24 mL||126.48 mL|
|0.5 mM||6.32 mL||31.62 mL||63.24 mL|
|2.5 mM||1.26 mL||6.32 mL||12.65 mL|
References are publications that support the biological activity of the product.
Manerba et al (2012) Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase. ChemMedChem 7 311 PMID: 22052811
Fiume et al (2013) Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells. Biochem.Biophys.Res.Commun. 430 466 PMID: 23237800
Farabegoli et al (2012) Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways. Eur.J.Pharm.Sci. 47 729 PMID: 22954722
If you know of a relevant reference for Galloflavin, please let us know.
View Related Products by Product Action
Keywords: Galloflavin, Galloflavin supplier, lactate, dehydrogenases, LDH-A, LDH-B, LDH, inhibitors, inhibits, aerobic, glycolysis, Lactate, Dehydrogenase, A, 4795, Tocris Bioscience
1 Citation for Galloflavin
Citations are publications that use Tocris products. Selected citations for Galloflavin include:
Kottakis et al (2016) LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature 539 390 PMID: 27799657
Do you know of a great paper that uses Galloflavin from Tocris? Please let us know.
Reviews for Galloflavin
Average Rating: 5 (Based on 1 Review.)
Have you used Galloflavin?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.