Biochemicals and Molecular Biology

Modulators

Cat. No. Product Name / Activity
8063 CHDI 113
Potent HTT pre-RNA splicing modulator

Ligands

Cat. No. Product Name / Activity
8042 Alkyne-cRGD
Integrin ligand for degrader development and targeted delivery, with alkyne click handle for conjugation

Building Blocks

Cat. No. Product Name / Activity
7921 DBCO-NHS
Amine reactive and azide reactive building block

Controls

Cat. No. Product Name / Activity
7789 IA
SHAPE-JuMP monoaduct control for TBIA (Cat.No. 7788)

Other

Cat. No. Product Name / Activity
6602 1M7
Reagent for RNA SHAPE-MaP chemistry
7376 2A3
Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
5113 AbK
Photo-crosslinking probe; unnatural amino acid
7936 Ac-Cys-NHMe
Building block for the lysine acylation using conjugating enzymes (LACE) technique
7932 Ac4GalN6yne
Alkyne containing monosaccharide building block; used in BOCTAG
8035 Ac4GalNAlk
Metabolic chemical reporter for studying glycosylation and glycoproteins
7479 Ac4ManNAz
Azide-containing monosaccharide building block; used as glycoprotein, glycolipid and glycoRNA probe
7553 Ac4ManNDAz
Photo-crosslinking probe for studying glycoproteins and glycolipids
3525 ACSF (Artificial Cerebrospinal Fluid)
Artificial cerebrospinal fluid (ACSF) for electrophysiology; sterile and microfiltered
6930 Amphotericin B
Forms monovalent ion channels in lipid bilyers; antifungal
5962 3-AP
Iron chelator; ribonucleotide reductase inhibitor
6834 Auxin
Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone
6584 L-Azidohomoalanine hydrochloride
Unnatural amino acid for bio-orthogonal labeling of newly synthesized proteins
6585 L-Azidonorleucine hydrochloride
Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins
2786 BAPTA
Selective calcium chelator
2787 BAPTA AM
Cell-permeable Ca2+ chelator
3349 Biocytin
Versatile marker for neuroanatomical investigations
6571 Biotin-11-dUTP
Biotin-labeled dUTP
6572 Biotin-LC-NAD+
Biotinylated analog of β-NAD+; commonly used reagent in LSD1 and PARP1 assays
6573 Biotin-NAD+
Biotinylated-NAD+; substrate for ADP-ribosylation
7524 Biotin-PEG3-Azide
Biotin with PEG linker and reactive click handle
5502 Blasticidin S HCl
Antibiotic; selection reagent for bis, bsr and BSD transformed cells
5015 5-BrdU
Synthetic thymidine analog; used for cell proliferation assays
5476 Cell Activation Cocktail 500X
Cell activation cocktail
7368 Cell Counting Kit-8
Cell viability and proliferation assay test solution
8108 CEP
Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells
7945 Cholesterol
Component of lipid nanoparticles (LNPs); modulator of lipid bilayer fluidity
6798 Click N-Acetylmuramic acid - alkyne
Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes
7506 Click N-Acetylmuramic acid - azide
Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes
3180 α-Cyclodextrin
Cyclic complexing agent
3181 β-Cyclodextrin
Cyclic complexing agent
7480 DBCO PEG4 Biotin
Biotinylation reagent for labeling azide-containing biomolecules via Cu(I)-free click chemistry
6175 DBHDA
Reagent for synthetic biology; converts cysteine to dehydroalanine
7176 DC-Cholesterol hydrochloride
Liposomal transfection reagent
5764 Deferoxamine mesylate
Iron chelator; also hypoxia mimetic and neuroprotectant
7768 Disulfide biotin azide
Azide-activated biotinylation reagent; labels alkyne moieties via copper-catalyzed click chemistry
3154 DL-Dithiothreitol
Maintains SH groups in the reduced state
7946 DLin-MC3-DMA
Ionizable cationic lipid
7944 DMG-PEG 2000
PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs)
3176 DMSO, sterile filtered
DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds
7726 DMSO, Cell Cryopreserve Grade
Intracellular cryoprotective agent
7175 DOPE
Liposome/lipoplex transfection enhancer
7179 DOTAP
Cationic agent for liposome and LNP formation
7943 DSPC
Neutral phospholipid; component of lipid nanoparticles (LNPs)
7947 DSPE-PEG 2000 Maleimide
PEGylated DSPE with a maleimide reactive group
6785 E 7820
Molecular glue; also α2 integrin inhibitor
2807 EGTA
Calcium chelating agent
7206 5-Ethynyluridine
Uridine analog, used for labeling RNA synthesis
6253 F 127 (20% solution in DMSO)
Nonionic detergent
8011 FAI
Reagent for RNA SHAPE-MaP experiments in live cells
6574 Fluorescein-NAD+
Fluorescent NAD+; substrate for ADP-ribosylation for use in PARP assays
7780 β-GalNAc-PEG4-Azide
Functionalized Asialoglycoprotein receptor ligand, for targeting conjugates to hepatocytes
4991 HaXS8
Chemical dimerizer
7046 1,6-Hexanediol
Tool for probing liquid-liquid phase separation
0708 2-Hydroxypropyl-β-cyclodextrin
Solubilization agent
7015 IA-Alkyne
Broad spectrum cysteine reactive probe
4299 iCRT 14
Transfection enhancer; also inhibits β-catenin-responsive transcription
6782 Indisulam
Molecular glue; pre-mRNA splicing modulator
5509 IPTG
Used in cloning procedures with X-GAL
6146 LAP
Photocrosslinker for hydrogels
7045 (±)-α-Lipoamide
Phase-separated condensate modifier; orally bioavailable
7044 (±)-α-Lipoic acid
Liquid-liquid phase separated condensate modifier; reduces stress granule formation
5427 D-Luciferin sodium salt
Firefly luciferase substrate
5224 MTT
Reagent used in the measurement of cell proliferation
5515 NADPH reduced form tetrasodium salt
Cofactor for many anabolic enzymes
7004 NAI
Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
7301 NHS-LC-Biotin
Amine reactive biotinylation reagent, cell permeable
7391 O-Propargyl-puromycin
Puromycin analog for labeling newly synthesized proteins
7974 P3S
Reagent for modifying RNA at 2'-OH position, for SHAPE-MAP experiments
7854 PEI STAR™ transfection reagent
Polyethylenimine (PEI) transfection reagent, chemically-defined
7739 Polyamine Supplement x1000 (lyophilized)
Media supplement; used as component of CEPT cocktail to enhance stem cell viability
7711 Polybrene
DNA transfection enhancer
7806 preQ1-alkyne
preQ1 with alkyne handle for click chemistry
7833 preQ1-azide
preQ1 with azide handle for click chemistry
7804 preQ1-biotin
PreQ1 with biotin handle for RNA labeling and purification
5500 Protease Inhibitor Cocktail I
Protease inhibitor cocktail for mammalian cells
8098 ProtiFect STAR™ Protein Transfection Reagent
Protein transfection reagent
1292 Rapamycin
Chemical dimerizer; also mTOR inhibitor
7723 RGD peptide
Directs association of cells with diverse biomaterials and surfaces
7302 Sulfo-NHS-LC-Biotin
Amine reactive biotinylation reagent, cell impermeable
7788 TBIA
Bivalent SHAPE cross-linking reagent
7862 TBTA
Click chemistry auxiliary reagent; stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reaction
7005 4-Thiouridine
Photoreactive uridine analog for RNA sequencing
7863 THPTA
Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction
6555 TokeOni
NIR-emission luciferin analog; ideal for deep tissue applications; orally bioavailable and brain penetrant
4309 TPEN
Cell-permeable Zn2+ chelator; also inhibits RNA binding protein Lin28