Modulators |
| Cat. No. |
Product Name / Activity |
| 8063 |
CHDI 113 |
| Potent HTT pre-RNA splicing modulator |
Ligands |
| Cat. No. |
Product Name / Activity |
| 8042 |
Alkyne-cRGD |
| Integrin ligand for degrader development and targeted delivery, with alkyne click handle for conjugation |
| 8869 |
ArMan New |
| DC-SIGN ligand used to target dendritic cells |
Building Blocks |
| Cat. No. |
Product Name / Activity |
| 7921 |
DBCO-NHS |
| Amine reactive and azide reactive building block |
| 7900 |
SCOTfluor 510 Fmoc-Dapa-OH |
| Fmoc protected fluorescent amino acid for use in solid-phase peptide synthesis to prepare PAINT imaging probes |
Controls |
| Cat. No. |
Product Name / Activity |
| 7789 |
IA |
| SHAPE-JuMP monoaduct control for TBIA (Cat.No. 7788) |
Other |
| Cat. No. |
Product Name / Activity |
| 6602 |
1M7 |
| Reagent for RNA SHAPE-MaP chemistry |
| 7376 |
2A3 |
| Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable |
| 5113 |
AbK |
| Photo-crosslinking probe; unnatural amino acid |
| 7936 |
Ac-Cys-NHMe |
| Building block for the lysine acylation using conjugating enzymes (LACE) technique |
| 7932 |
Ac4GalN6yne |
| Alkyne containing monosaccharide building block; used in BOCTAG |
| 8035 |
Ac4GalNAlk |
| Metabolic chemical reporter for studying glycosylation and glycoproteins |
| 7479 |
Ac4ManNAz |
| Azide-containing monosaccharide building block; used as glycoprotein, glycolipid and glycoRNA probe |
| 7553 |
Ac4ManNDAz |
| Photo-crosslinking probe for studying glycoproteins and glycolipids |
| 3525 |
ACSF (Artificial Cerebrospinal Fluid) |
| Artificial cerebrospinal fluid (ACSF) for electrophysiology; sterile and microfiltered |
| 6930 |
Amphotericin B |
| Forms monovalent ion channels in lipid bilyers; antifungal |
| 6834 |
Auxin |
| Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone |
| 6584 |
L-Azidohomoalanine hydrochloride |
| Unnatural amino acid for bio-orthogonal labeling of newly synthesized proteins |
| 6585 |
L-Azidonorleucine hydrochloride |
| Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins |
| 2786 |
BAPTA |
| Selective calcium chelator |
| 2787 |
BAPTA AM |
| Cell-permeable Ca2+ chelator |
| 3349 |
Biocytin |
| Versatile marker for neuroanatomical investigations |
| 6571 |
Biotin-11-dUTP |
| Biotin-labeled dUTP |
| 6573 |
Biotin-NAD+ |
| Biotinylated-NAD+; substrate for ADP-ribosylation |
| 7524 |
Biotin-PEG3-Azide |
| Biotin with PEG linker and reactive click handle |
| 5502 |
Blasticidin S HCl |
| Antibiotic; selection reagent for bis, bsr and BSD transformed cells |
| 5015 |
5-BrdU |
| Synthetic thymidine analog; used for cell proliferation assays |
| 8059 |
BTD S-sulfenic acid probe |
| Chemoproteomic reagent for targeting S-sulfenic acids on SulfenQ platform, alkyne handle for click chemistry |
| 5476 |
Cell Activation Cocktail 500X |
| Cell activation cocktail |
| 7368 |
Cell Counting Kit-8 |
| Cell viability and proliferation assay test solution |
| 8108 |
CEP |
| Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells |
| 7769 |
Chem-CLIP control probe |
| Control probe for Chem-CLIP experiments |
| 7945 |
Cholesterol |
| Component of lipid nanoparticles (LNPs); modulator of lipid bilayer fluidity |
| 6798 |
Click N-Acetylmuramic acid - alkyne |
| Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes |
| 7506 |
Click N-Acetylmuramic acid - azide |
| Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes |
| 3180 |
α-Cyclodextrin |
| Cyclic complexing agent |
| 3181 |
β-Cyclodextrin |
| Cyclic complexing agent |
| 7480 |
DBCO PEG4 Biotin |
| Biotinylation reagent for labeling azide-containing biomolecules via Cu(I)-free click chemistry |
| 6175 |
DBHDA |
| Reagent for synthetic biology; converts cysteine to dehydroalanine |
| 7176 |
DC-Cholesterol hydrochloride |
| Liposomal transfection reagent |
| 5764 |
Deferoxamine mesylate |
| Iron chelator; also hypoxia mimetic and neuroprotectant |
| 7784 |
Digoxigenin NHS ester New |
| NHS ester hapten for labeling amino groups |
| 7768 |
Disulfide biotin azide |
| Azide-activated biotinylation reagent; labels alkyne moieties via copper-catalyzed click chemistry |
| 3154 |
DL-Dithiothreitol |
| Maintains SH groups in the reduced state |
| 8895 |
DLin-KC2-DMA New |
| Ionizable cationic lipid |
| 7946 |
DLin-MC3-DMA |
| Ionizable cationic lipid |
| 7944 |
DMG-PEG 2000 |
| PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs) |
| 3176 |
DMSO, sterile filtered |
| DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds |
| 7726 |
DMSO, Cell Cryopreserve Grade |
| Intracellular cryoprotective agent |
| 7175 |
DOPE |
| Liposome/lipoplex transfection enhancer |
| 7179 |
DOTAP |
| Cationic agent for liposome and LNP formation |
| 7943 |
DSPC |
| Neutral phospholipid; component of lipid nanoparticles (LNPs) |
| 8837 |
DSPE-PEG 2000 Azide New |
| PEGylated DSPE with azide reactive group |
| 8838 |
DSPE-PEG 2000 Biotin New |
| Biotinylated DSPE PEG lipid |
| 7947 |
DSPE-PEG 2000 Maleimide |
| PEGylated DSPE with a maleimide reactive group |
| 6785 |
E 7820 |
| Molecular glue; also α2 integrin inhibitor |
| 2807 |
EGTA |
| Calcium chelating agent |
| 7206 |
5-Ethynyluridine |
| Uridine analog, used for labeling RNA synthesis |
| 6253 |
F 127 (20% solution in DMSO) |
| Nonionic detergent |
| 8011 |
FAI |
| Reagent for RNA SHAPE-MaP experiments in live cells |
| 6574 |
Fluorescein-NAD+ |
| Fluorescent NAD+; substrate for ADP-ribosylation for use in PARP assays |
| 7780 |
β-GalNAc-PEG4-Azide |
| Functionalized Asialoglycoprotein receptor ligand, for targeting conjugates to hepatocytes |
| 4991 |
HaXS8 |
| Chemical dimerizer |
| 7046 |
1,6-Hexanediol |
| Tool for probing liquid-liquid phase separation |
| 0708 |
2-Hydroxypropyl-β-cyclodextrin |
| Solubilization agent |
| 7015 |
IA-Alkyne |
| Broad spectrum cysteine reactive probe |
| 4299 |
iCRT 14 |
| Transfection enhancer; also inhibits β-catenin-responsive transcription |
| 6782 |
Indisulam |
| Molecular glue; pre-mRNA splicing modulator |
| 5509 |
IPTG |
| Used in cloning procedures with X-GAL |
| 8888 |
LaKe New |
| Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells |
| 6146 |
LAP |
| Photocrosslinker for hydrogels |
| 5427 |
D-Luciferin sodium salt |
| Firefly luciferase substrate |
| 8889 |
MC3 LNP Luciferase New |
| Dlin-MC3 containing LNP for in vitro and in vivo delivery of luciferase mRNA |
| 5224 |
MTT |
| Reagent used in the measurement of cell proliferation |
| 5515 |
NADPH reduced form tetrasodium salt |
| Cofactor for many anabolic enzymes |
| 7004 |
NAI |
| Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable |
| 7391 |
O-Propargyl-puromycin |
| Puromycin analog for labeling newly synthesized proteins |
| 7974 |
P3S |
| Reagent for modifying RNA at 2'-OH position, for SHAPE-MAP experiments |
| 7854 |
PEI STAR™ transfection reagent |
| Polyethylenimine (PEI) transfection reagent, chemically-defined |
| 8174 |
PEI STAR-Go™ transfection reagent |
| Aqueous solution of polyethylenimine (PEI) transfection reagent |
| 7739 |
Polyamine Supplement x1000 (lyophilized) |
| Media supplement; used as component of CEPT cocktail to enhance stem cell viability |
| 7711 |
Polybrene |
| DNA transfection enhancer |
| 7806 |
preQ1-alkyne |
| preQ1 with alkyne handle for click chemistry |
| 7833 |
preQ1-azide |
| preQ1 with azide handle for click chemistry |
| 7804 |
preQ1-biotin |
| PreQ1 with biotin handle for RNA labeling and purification |
| 5500 |
Protease Inhibitor Cocktail I |
| Protease inhibitor cocktail for mammalian cells |
| 8098 |
ProtiFect STAR™ Protein Transfection Reagent |
| Protein transfection reagent |
| 1292 |
Rapamycin |
| Chemical dimerizer; also mTOR inhibitor |
| 7723 |
RGD peptide |
| Directs association of cells with diverse biomaterials and surfaces |
| 8909 |
SM 102 New |
| Cationic ionizable lipid |
| 7302 |
Sulfo-NHS-LC-Biotin |
| Amine reactive biotinylation reagent, cell impermeable |
| 7788 |
TBIA |
| Bivalent SHAPE cross-linking reagent |
| 7862 |
TBTA |
| Click chemistry auxiliary reagent; stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reaction |
| 7005 |
4-Thiouridine |
| Photoreactive uridine analog for RNA sequencing |
| 7863 |
THPTA |
| Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction |
| 6555 |
TokeOni |
| NIR-emission luciferin analog; ideal for deep tissue applications; orally bioavailable and brain penetrant |
| 4309 |
TPEN |
| Cell-permeable Zn2+ chelator; also inhibits RNA binding protein Lin28 |