You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for preQ1-biotin
preQ1-biotin is is a modified analog of the natural substrate prequeosine1 (preQ1). preQ1-biotin enables affinity tagging and pull-down of specific RNAs that have been modified selectively by E. coli tRNA guanine transglycosylase (TGT). preQ1-biotin is incorporated site-specifically and covalently into RNAs containing a short harpin nucleotide recognition motif. The guanine in a UGU recognition element is exchanged with the preQ1-biotin substrate.
Sold under license from The Regents of the University of California.
Technical Data for preQ1-biotin
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for preQ1-biotin
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for preQ1-biotin
The following data is based on the product molecular weight 504.65. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||9.91 mL||49.54 mL||99.08 mL|
|1 mM||1.98 mL||9.91 mL||19.82 mL|
|2 mM||0.99 mL||4.95 mL||9.91 mL|
|10 mM||0.2 mL||0.99 mL||1.98 mL|
References for preQ1-biotin
References are publications that support the biological activity of the product.
Busby et al (2020) Enzymatic RNA biotinylation for affinity purification and identification of RNA-protein interactions. ACS Chem.Biol. 15 2247 PMID: 32706237
If you know of a relevant reference for preQ1-biotin, please let us know.
View Related Products by Target
Keywords: preQ1-biotin, preQ1-biotin supplier, preq1biotin, prequeosine1, RNA, binding, labeling, purification, TGT, Biochemicals, and, Molecular, Biology, 7804, Tocris Bioscience
Citations for preQ1-biotin
Citations are publications that use Tocris products.
Currently there are no citations for preQ1-biotin. Do you know of a great paper that uses preQ1-biotin from Tocris? Please let us know.
Reviews for preQ1-biotin
There are currently no reviews for this product. Be the first to review preQ1-biotin and earn rewards!
Have you used preQ1-biotin?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image