Biotin-11-dUTP

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Cat.No. 6571 - Biotin-11-dUTP | C28H45N6O17P3S.4(C2H5)3N
Description: Biotin-labeled dUTP
Chemical Name: 2'-Deoxy-5-[(1E)-3-[[6-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-1-oxohexyl]amino]-1-propen-1-yl]uridine 5'-(tetra(triethylammonium) triphosphate)
Purity: ≥95% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Biotin-labeled dUTP. Commonly used in PCR, nick translation, and reverse transcription. Also frequently used in apoptosis assays. Biotin-labeled DNA may be detected with streptavidin-HRP conjugates.

Technical Data

M. Wt 1267.43
Formula C28H45N6O17P3S.4(C2H5)3N
Storage Store at -20°C
Purity ≥95% (HPLC)
PubChem ID 101939310
InChI Key AZRNEVJSOSKAOC-PEFKSLAVSA-N
Smiles [H][C@]12CS[C@H]([C@]1(NC(N2)=O)[H])CCCCC(NCCCCCC(NC/C=C/C3=CN(C(NC3=O)=O)[C@H]4C[C@@H]([C@H](O4)COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O)=O)=O.CC[N+]([H])(CC)CC.CC[N+]([H])(CC)CC.CC[N+]([H])(CC)CC.CC[N+]([H])(CC)CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 1 mM in 10mM Tris-HCl buffer (supplied pre-dissolved - 1mM)

References

References are publications that support the biological activity of the product.

Jun-Hyuk Choi et al (2015) An integrated approach for analysis of the DNA damage response in mammalian cells J.Biol.Chem. 290 2881 PMID: 26438822


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Citations for Biotin-11-dUTP

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Literature in this Area

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