The most widely used modified cyclodextrin, the lipophilic cavity formed by 7 glucose units. Drug solubility in water is greatly enhanced by complexing with HBC.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 1400. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.71 mL||3.57 mL||7.14 mL|
|5 mM||0.14 mL||0.71 mL||1.43 mL|
|10 mM||0.07 mL||0.36 mL||0.71 mL|
|50 mM||0.01 mL||0.07 mL||0.14 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Frijlink (1991) The effects of cyclodextrins on the disposition of intravenously injected drugs in the rat. Pharm.Res. 8 380 PMID: 2052529
If you know of a relevant reference for 2-Hydroxypropyl-β-cyclodextrin, please let us know.
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Keywords: Hydroxypropyl-b-cyclodextrin, supplier, Solubilization, agent, Reagents, cyclodextrin, Hydroxypropyl-beta-cyclodextrin, Hydroxypropyl-β-cyclodextrin, HBC, Hydroxypropyl-b-cyclodextrin, Biochemicals, and, Molecular, Biology, Tocris Bioscience
1 Citation for 2-Hydroxypropyl-β-cyclodextrin
Citations are publications that use Tocris products. Selected citations for 2-Hydroxypropyl-β-cyclodextrin include:
Johnson et al (2012) Orexin 1 receptors are a novel target to modulate panic responses and the panic brain network. Proc Natl Acad Sci U S A 107 733 PMID: 22554617
Do you know of a great paper that uses 2-Hydroxypropyl-β-cyclodextrin from Tocris? If so please let us know.
Literature in this Area
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