18A

Cat. No. 5612

18A C14H11N5O2S [331261-50-8]

Price and Availability

For 18A pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: N-2,1,3-Benzothiadiazol-4-yl-2-[(4-hydroxyphenyl)methylene]-hydrazinecarboxamide

Biological Activity

HIV cell entry blocker. Binds gp120 and inhibits cell entry for a broad spectrum of HIV isolates. Exhibits no effect on the binding of CD4 or CCR5.

Technical Data

M.Wt:
313.33
Formula:
C14H11N5O2S
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
331261-50-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Herschhorn et al (2014) A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry. Nat.Chem.Biol. 10 845. PMID: 25174000.

If you know of a relevant reference for 18A please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses 18A from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: 18A, supplier, Tocris Bioscience, Antiviral products

Quick Order

Find multiple products by catalog number

divider line

Immunology Guide

Immunology Product Listing

Our Immunology listing highlights over 190 products for immunology research. Request copy or view PDF today.

divider line

New Products in this Area

Nanchangmycin

Antiviral; active against Zika, West Nile and dengue viruses

25-Hydroxycholesterol

Antiviral; also α-crystallin (cryAB) chaperone

Filipin III

Polyene antibiotic; inhibits formation of pathological isoform of prion protein

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.