18A

Cat. No. 5612

18A C14H11N5O2S [331261-50-8]

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Chemical Name: N-2,1,3-Benzothiadiazol-4-yl-2-[(4-hydroxyphenyl)methylene]-hydrazinecarboxamide

Biological Activity

HIV cell entry blocker. Binds gp120 and inhibits cell entry for a broad spectrum of HIV isolates. Exhibits no effect on the binding of CD4 or CCR5.

Technical Data

M.Wt:
313.33
Formula:
C14H11N5O2S
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
331261-50-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Herschhorn et al (2014) A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry. Nat.Chem.Biol. 10 845. PMID: 25174000.

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