DNA, RNA and Protein Synthesis Inhibitors

Cat. No. Product Name / Activity
4215 4E1RCat
Protein translation inhibitor; blocks eIF4F subunit interaction
4800 4EGI-1
Inhibitor of eIF4E:eIF4G interaction
1229 Actinomycin D
RNA polymerase inhibitor
2513 Acyclovir
Viral DNA polymerase inhibitor
4025 α-Amanitin
Inhibitor of RNA polymerase II
1290 Anisomycin
Protein synthesis inhibitor
5736 Aphidicolin
DNA polymerase α, δ and ε inhibitor
6392 B02
RAD51 recombinase inhibitor
2981 BIBR 1532
Selective telomerase inhibitor
5417 BMH 21
RNA polymerase 1 inhibitor; also p53 pathway activator
5312 BRACO 19 trihydrochloride
Telomerase inhibitor
6196 Brequinar sodium
Potent and selective DHODH inhibitor
4799 Capecitabine
Prodrug of 5-Fluorouracil (Cat. No. 3257). Inhibits DNA synthesis
2626 Carboplatin
Inhibitor of DNA synthesis
4436 8-Chloroadenosine
Cytotoxic nucleoside analog; inhibits RNA synthesis
2294 Cordycepin
RNA synthesis inhibitor
2483 Costunolide
Inhibitor of human telomerase activity
0970 Cycloheximide
Inhibitor of protein synthesis
4520 Cytarabine
Nucleoside analog; inhibits DNA replication
3917 Daptomycin
Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria
1467 Daunorubicin hydrochloride
RNA synthesis inhibitor
3857 Dexrazoxane hydrochloride
Topoisomerase II inhibitor
3260 Epirubicin hydrochloride
Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
4659 Floxuridine
Disrupts DNA replication; inhibits thymidylate synthetase
3495 Fludarabine
Purine analog; inhibits DNA synthesis
3257 5-Fluorouracil
Inhibits RNA and DNA synthesis
4131 G418 disulfate salt
Aminoglycoside antibiotic; used in cell culture
3259 Gemcitabine hydrochloride
DNA synthesis inhibitor
1993 Halofuginone hydrobromide
High affinity competitive prolyl-tRNA synthetase inhibitor
1416 Homoharringtonine
Inhibitor of protein synthesis; antileukemic agent
5740 6-Hydroxy-DL-DOPA
Allosteric inhibitor of RAD52; also APE1 inhibitor
6483 Isoginkgetin
Pre-mRNA splicing inhibitor; cell permeable
7338 K 22
Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation
6068 Lin28 1632
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
3765 Linezolid
Antibiotic; inhibits protein synthesis in gram-positive bacteria
6510 LNT 1
Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response
6819 Mefloquine hydrochloride
Binds 80S ribosome and inhibits protein synthesis in P falciparum; also gap junction blocker
4103 6-Mercaptopurine
Purine analog; inhibits DNA and RNA synthesis
1489 Mithramycin A
Inhibitor of DNA and RNA polymerase
3258 Mitomycin C
Inhibitor of DNA synthesis
6359 Nelarabine
Purine nuceloside analog; inhibits DNA synthesis
5340 NSC 617145
Werner syndrome helicase (WRN) inhibitor
2623 Oxaliplatin
Inhibitor of DNA synthesis
5419 PCNA I1
PCNA inhibitor
6222 PFM 01
MRE11 endonuclease inhibitor
6070 Pladienolide B
mRNA splicing inhibitor; antitumor
4089 Puromycin dihydrochloride
Protein synthesis inhibitor
6168 RI 1
RAD51 recombinase inhibitor
4501 Ribavirin
Antiviral guanosine analog; blocks eIF4E activity
4121 Rifampicin
Antibiotic; inhibits bacterial RNA polymerase
4723 T2AA
PCNA inhibitor
6884 TC SL C5
Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) RNA inhibitor
5069 Teriflunomide
Inhibitor of DHODH; active metabolite of Leflunomide
3267 Thiostrepton
Antibiotic, inhibits protein synthesis
4309 TPEN
RNA binding protein Lin28 inhibitor; cell-permeable Zn2+ chelator
3253 Triptolide
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
3863 Trovafloxacin mesylate
Antibiotic; inhibits bacterial DNA synthesis
3787 Viomycin
Antibiotic; inhibits bacterial DNA synthesis
4067 YK 4-279
Inhibitor of RNA helicase A (RHA)