DNA, RNA and Protein Synthesis Inhibitors

Cat. No.	Product Name / Activity
4800	4EGI-1
	Inhibitor of eIF4E:eIF4G interaction
1229	Actinomycin D
	RNA polymerase inhibitor
2513	Acyclovir
	Viral DNA polymerase inhibitor
4025	α-Amanitin
	Inhibitor of RNA polymerase II
1290	Anisomycin
	Protein synthesis inhibitor
5736	Aphidicolin
	DNA polymerase α, δ and ε inhibitor
6392	B02
	RAD51 recombinase inhibitor
2981	BIBR 1532
	Selective telomerase inhibitor
5417	BMH 21
	RNA polymerase 1 inhibitor; also p53 pathway activator
5312	BRACO 19 trihydrochloride
	Telomerase inhibitor
6196	Brequinar sodium
	Potent and selective DHODH inhibitor
7457	CAM 833
	Selective orthosteric inhibitor of the BRCA2-RAD51 interaction
4799	Capecitabine
	Prodrug of 5-Fluorouracil (Cat. No. 3257). Inhibits DNA synthesis
2626	Carboplatin
	Inhibitor of DNA synthesis
4436	8-Chloroadenosine
	Cytotoxic nucleoside analog; inhibits RNA synthesis
2294	Cordycepin
	RNA synthesis inhibitor
7485	Covidcil-19
	Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency
0970	Cycloheximide
	Inhibitor of protein synthesis
4520	Cytarabine
	Nucleoside analog; inhibits DNA replication
3917	Daptomycin
	Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria
1467	Daunorubicin hydrochloride
	RNA synthesis inhibitor
3857	Dexrazoxane hydrochloride
	Topoisomerase II inhibitor
7342	Emetine dihydrochloride
	RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika
3260	Epirubicin hydrochloride
	Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
4659	Floxuridine
	Disrupts DNA replication; inhibits thymidylate synthetase
3495	Fludarabine
	Purine analog; inhibits DNA synthesis
3257	5-Fluorouracil
	Inhibits RNA and DNA synthesis
4131	G418 disulfate salt
	Aminoglycoside antibiotic; used in cell culture
3259	Gemcitabine hydrochloride
	DNA synthesis inhibitor
1993	Halofuginone hydrobromide
	High affinity competitive prolyl-tRNA synthetase inhibitor
1416	Homoharringtonine
	Inhibitor of protein synthesis; antileukemic agent
5740	6-Hydroxy-DL-DOPA
	Allosteric inhibitor of RAD52; also APE1 inhibitor
6483	Isoginkgetin
	Pre-mRNA splicing inhibitor; cell permeable
7338	K 22
	Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation
6068	Lin28 1632
	RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
3765	Linezolid
	Antibiotic; inhibits protein synthesis in gram-positive bacteria
6510	LNT 1
	Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response
6819	Mefloquine hydrochloride
	Binds 80S ribosome and inhibits protein synthesis in P falciparum; also gap junction blocker
4103	6-Mercaptopurine
	Purine analog; inhibits DNA and RNA synthesis
1489	Mithramycin A
	Inhibitor of DNA and RNA polymerase
3258	Mitomycin C
	Inhibitor of DNA synthesis
6359	Nelarabine
	Purine nuceloside analog; inhibits DNA synthesis
5340	NSC 617145
	Werner syndrome helicase (WRN) inhibitor
2623	Oxaliplatin
	Inhibitor of DNA synthesis
6222	PFM 01
	MRE11 endonuclease inhibitor
6070	Pladienolide B
	mRNA splicing inhibitor; antitumor
7321	Pritelivir
	Potent and selective herpes simplex virus (HSV) helicase primase inhibitor
4089	Puromycin dihydrochloride
	Protein synthesis inhibitor
4501	Ribavirin
	Antiviral guanosine analog; blocks eIF4E activity
4121	Rifampicin
	Antibiotic; inhibits bacterial RNA polymerase
7760	Selinexor New
	Selective exportin 1 (XPO1/CRM1) inhibitor
7554	SSYA10-001
	Inhibits coronavirus helicase; blocks unwinding activity of Nsp13 and RNA synthesis
4723	T2AA
	PCNA inhibitor
6884	TC SL C5
	Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) RNA inhibitor
5069	Teriflunomide
	Inhibitor of DHODH; active metabolite of Leflunomide
4309	TPEN
	RNA binding protein Lin28 inhibitor; cell-permeable Zn²⁺ chelator
3253	Triptolide
	Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
3863	Trovafloxacin mesylate
	Antibiotic; inhibits bacterial DNA synthesis
7569	Verdinexor
	Selective exportin-1 (XPO1/CRM1) inhibitor
3787	Viomycin
	Antibiotic; inhibits bacterial DNA synthesis
4067	YK 4-279
	Inhibitor of RNA helicase A (RHA)