Cat. No. | Product Name / Activity |
---|---|
3336 | A 769662 |
Autophagy activator; potent AMPK activator | |
1234 | A23187, free acid |
Causes ER stress; can be used to induce autophagy in mammalian cells | |
7680 | ABT 263 |
Induces autophagy; Bcl-2 family inhibitor | |
4095 | Amiodarone hydrochloride |
Causes mitochondrial fragmentation and cell death; stimulates autophagy | |
7699 | AUTAC4 New |
Autophagy-targeting Degrader; targets dysfuntional mitochondria for degradation; ligand of the translocator protein (TSPO) | |
1231 | Brefeldin A |
Causes ER stress; induces autophagy in mammalian cells | |
4098 | Carbamazepine |
Induces autophagy by inhibiting inositol synthesis; Inhibits neuronal NaV channels | |
0690 | Clonidine hydrochloride |
α2 agonist and I1 ligand; thought to enhance autophagy | |
1126 | Dexamethasone |
Anti-inflammatory glucocorticoid; also induces autophagy in ALL cell lines | |
3093 | Dorsomorphin dihydrochloride |
Induces autophagy via an AMPK inhibition-independent mechanism | |
7474 | EN6 |
Activator of autophagy; inactivates mTORC1 signaling | |
6188 | Everolimus |
Autophagy activator; mTOR inhibitor | |
4808 | FK 866 hydrochloride |
Non-competitive and potent NAMPT inhibitor; induces apoptosis and autophagy | |
0741 | GF 109203X |
Protein kinase C inhibitor | |
0681 | L-690,330 |
Inositol monophosphatase inhibitor; induces autophagy independently of mTOR inhibition | |
6617 | LYN 1604 dihydrochloride |
Induces autophagy; ULK1 agonist | |
2864 | Metformin hydrochloride |
Activator of LKB1/AMPK; activates autophagy | |
1391 | NF 449 |
Highly selective P2X1 antagonist; Gsα-selective antagonist | |
4079 | Niclosamide |
STAT3 inhibitor; also inhibits mTORC1 signaling. Stimulates autophagy in vitro | |
0600 | Nimodipine |
Induces autophagy; Ca2+ channel blocker (L-type) | |
0601 | Nitrendipine |
Induces autophagy; Ca2+ channel blocker (L-type) | |
6087 | Perifosine |
PKB/Akt inhibitor; induces autophagy | |
2930 | PI 103 hydrochloride |
Inhibitor of PI 3-kinase, mTOR and DNA-PK | |
1267 | Pifithrin-α hydrobromide |
p53 inhibitor | |
1292 | Rapamycin |
mTOR inhibitor; induces autophagy | |
1418 | Resveratrol |
Autophagy activator; also cyclooxygenase inhibitor | |
0695 | Retinoic acid |
Autophagy activator; also endogenous retinoic acid receptor agonist | |
0790 | Rilmenidine hemifumarate |
α2 agonist and I1 ligand; thought to enhance autophagy | |
1610 | Rottlerin |
Stimulates autophagy | |
4652 | SAHA |
Autophagy activator; also Class I and II HDAC inhibitor | |
4297 | SMER 28 |
Positive regulator of autophagy | |
7558 | SRT 1720 |
Induces autophagy; SIRT1 activator | |
2706 | Temozolomide |
DNA-methylating antitumor agent; also induces autophagy | |
5264 | Temsirolimus |
Autophagy activator; mTOR inhibitor | |
1138 | Thapsigargin |
Causes ER stress; can be used to induce autophagy in mammalian cells | |
4247 | Torin 1 |
Potent and selective mTOR inhibitor; induces autophagy in HeLa cells | |
4248 | Torin 2 |
Autophagy activator; also potent and selective mTOR inhibitor | |
1406 | Trichostatin A |
Autophagy activator; potent histone deacetylase inhibitor | |
3516 | Tunicamycin |
Causes ER stress; can be used to induce autophagy | |
2815 | Valproic acid, sodium salt |
Reduces inositol levels; induces autophagy | |
0654 | Verapamil hydrochloride |
Ca2+ channel blocker (L-type); induces autophagy | |
7878 | XIE62-1004 New |
Inducer of autophagy via interaction of p62 and LC3 |