New ProductsView all New Products by pharmacological action
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| 8975 | D 927 | Jul 2026 |
Histone Deacetylase (HDAC) Degraders | ||
| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 8024 | CT-4 | Jun 2026 |
| Potent and selective HDAC8 degrader (PROTAC®) | ||
Voltage-gated Sodium (NaV) Channels | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8865 | LTGO-33 | Mar 2026 |
| Potent and selective state-independent inhibitor of NaV1.8 sodium channels | ||
Class III HDACs (Sirtuins) | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8979 | SKLB-11A | Jul 2026 |
| Potent and selective allosteric activator of SIRT3 | ||
Tyramide Signal Amplification (TSA) | ||
| Cat. No. | Product Name / Activity | Date Added |
| 9007 | ClariTSA™ Fluorophore Kit 690 | Jun 2026 |
| Signal amplification kit for use in ISH, ICC and IHC | ||
| 9022 | ClariTSA™ Fluorophore Kit 620 | Jun 2026 |
| Signal amplification kit for use in ISH, ICC and IHC | ||
Glucagon-Like Peptide 1 Receptors | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8946 | Semaglutide | May 2026 |
| Highly potent, long-acting GLP-1 receptor agonist | ||
Casein Kinase 2 | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8993 | CX-4945 | Feb 2026 |
| Potent and selective CK2α and CK2α' inhibitor. Also blocks CK2-dependent HIF-1α transcription, causes cell-cycle arrest, induces apoptosis in cancer cells and induces stem cell reprogramming | ||
Glycogen Synthase Kinase 3 | ||
| Cat. No. | Product Name / Activity | Date Added |
| 3673 | 1-Azakenpaullone | May 2026 |
| Potent and selective GSK3 inhibitor. Used in chemical cocktail for induction and maintainance of TotiSCs. | ||
CBP and p300 Degraders | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8843 | MC 1 | Jul 2026 |
| Selective EP300 Degrader (PROTAC®) | ||
Poly(ADP-ribose) Polymerase | ||
| Cat. No. | Product Name / Activity | Date Added |
| 9003 | RBN-2397 | Jun 2026 |
| Potent and selective PARP7 inhibitor; induces antitumor immunity. | ||
Amine-Reactive Janelia Fluor® Dyes | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8983 | Janelia Fluor® 570, NHS ester | Mar 2026 |
| Orange dye (Reactive group: NHS ester). Application: Suitable for live cell imaging | ||
Ancillary Material Grade Small Molecules | ||
| Cat. No. | Product Name / Activity | Date Added |
| TB6476-RMU | Compound E | May 2026 |
| Compound E synthesized to Ancillary Material Grade | ||
| TB1141-RMU | Dibutyryl-cAMP, sodium salt | May 2026 |
| Dibutyryl-cAMP, sodium salt synthesized to Ancillary Material Grade | ||
Aptamer-based RNA Imaging | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8974 | SALAD1 | Apr 2026 |
| Ultrabright fluorogenic dye for imaging RNA in living cells; activated by binding Mango aptamers | ||
Fluorescent Probes for Imaging Bacteria | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8967 | Janelia Fluor® 646 Tre | Jul 2026 |
| Red fluorescent trehalose probe for live mycobacteria imaging | ||
Biochemicals and Molecular Biology | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8994 | Biotin-PEG4-Diazirine | Mar 2026 |
| Photo-crosslinking capture probe for deazaflavin-diazirine energy-transfer labelling (DarT labelling) with a biotin handle | ||
| 9028 | SEQURNA | Jul 2026 |
| Synthetic thermostable RNase inhibitor for single-cell RNA-sequencing (scRNAseq) | ||
| 7790 | Ovalbumin peptide (257-264) | Jun 2026 |
| Immunogenic glycoprotein used as model antigen for immunization and vaccination research. | ||
| 7966 | DADPS Biotin Azide | Jun 2026 |
| Acid cleavable biotin capture reagent, with an azide group as a click handle for conjugation | ||
| 8910 | NAIA | Feb 2026 |
| Broad spectrum cysteine reactive probe; suitable for live-cell applications | ||
BromoCatch™ Platform | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8942 | Janelia Fluor® 549, BromoCatch™ Ligand | Feb 2026 |
| Fluorogenic Janelia Fluor® 549 conjugated covalent ligand for BromoCatch™, enabling no-wash live-cell imaging | ||
Live-cell Imaging | ||
| Cat. No. | Product Name / Activity | Date Added |
| 9042 | LipoLIVE™ Deep Red Non-Toxic Dye | Jul 2026 |
| Ready-to-use fluorescent probe for the real-time visualization of lipid droplet dynamics in living cells | ||
| 9026 | LipoLIVE™ Green Non-Toxic Dye | Mar 2026 |
| Ready-to-use fluorescent probe for the real-time visualization of lipid droplet dynamics in living cells | ||
| 9034 | SPiDER-βGal Cellular Senescence Dye | Jun 2026 |
| Fluorogenic β-galactosidase substrate suitable for live/fixed cells and tissues imaging. | ||
Checkpoint Control Kinases | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8969 | AM 9022 | Jul 2026 |
| Potent and selective KIF18A inhibitor | ||
| 8955 | BBI 2779 | Jul 2026 |
| Potent and selective CHK1 inhibitor | ||
Other Degraders | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8919 | MS 41 | Jul 2026 |
| Potent and selective degrader of Eleven-Nineteen Leukemia (ENL) | ||
| 8968 | XL01126 | Jul 2026 |
| Potent and selective degrader of LRRK2 | ||
Deubiquitinating Enzymes | ||
| Cat. No. | Product Name / Activity | Date Added |
| 7746 | KSQ 4279 | Feb 2026 |
| Potent and selective USP1 allosteric inhibitor | ||
DNA, RNA and Protein Synthesis | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8803 | ASP 7967 | Feb 2026 |
| Ligand for RNA aptamer AC17-4 activating gene expression in aptazime-based riboswitches | ||
| 7147 | Bleomycin sulfate | Feb 2026 |
| DNA synthesis inhibitor. Induces pulmonary inflammation and fibrosis | ||
| 7416 | Plitidepsin | Mar 2026 |
| Potent protein synthesis inhibitor | ||
| 9027 | VVD-214 | May 2026 |
| Potent WRN covalent allosteric inhibitor; orally bioavailable | ||
Sulfhydryl-Reactive Janelia Fluor® Dyes | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8026 | Janelia Fluor® 585, Maleimide | Jun 2026 |
| Orange dye (Reactive group: maleimide). Application: flow cytometry, confocal microscopy, super resolution microscopy including dSTORM & STED. Suitable for live cell imaging | ||
Fluorescent Ion Indicators | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8846 | FerroOrange | Feb 2026 |
| Sensitive and cell-permeable fluorogenic probe for the detection of labile Fe(II) in live cells; suitable for high-throughput assays | ||
Ras GTPases | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8952 | VVD 844 | Feb 2026 |
| Potent covalent inhibitor of the RAS domain of the PI3K/p110α interaction | ||
Inflammasomes | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8894 | NP3-253 | Jul 2026 |
| Potent brain penetrant inhibitor of the NLRP3 inflammasome | ||
Self-labeling Tags | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8948 | Janelia Fluor® 552, Haloalkane | Mar 2026 |
| Cell-permeable fluorogenic dye with a chloroalkane handle. Application: live-cell imaging as a self-labeling tag substrate. Also chemigenetic Ca2+ indicator. | ||
Lipid Nanoparticles | ||
| Cat. No. | Product Name / Activity | Date Added |
| 9000 | RiboDyEE™ | May 2026 |
| Fluorescent dye for quantification of RNA in LNP encapsulation efficiency assays (1 Pack/5x120μL) | ||
Other Lysine Methyltransferases | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8907 | SNDX-5613 | Jul 2026 |
| Menin-MLL interaction inhibitor | ||
Other Notch Signaling | ||
| Cat. No. | Product Name / Activity | Date Added |
| 9002 | CB-103 | Jun 2026 |
| pan-Notch inhibitor; also inhibits differentiation of mural cells by downregulating Notch pathway. | ||
μ Opioid Receptors | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8984 | β-Lipotropin 61-91 | May 2026 |
| Endogenous opioid peptide; component of the LIP cocktail for preconditioning human β-cells | ||
κ Opioid Receptors | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8135 | PIPE 3297 dihydrochloride | Mar 2026 |
| Potent and selective κ opioid receptor agonist; devoid of β-Arrestin-2 recruitment. Also induces differentiation of OPC. | ||
Protein Ser/Thr Phosphatases | ||
| Cat. No. | Product Name / Activity | Date Added |
| 9012 | Okadaic acid ammonium salt | Feb 2026 |
| Protein phosphatase 1 and 2A inhibitor | ||
Pregnane X Receptors | ||
| Cat. No. | Product Name / Activity | Date Added |
| 8840 | SJPYT 328 | Jun 2026 |
| Potent and selective PXR1 agonist | ||