New Products

View all New Products by pharmacological action

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Adrenergic α2 Receptors

Cat. No. Product Name / Activity Date Added
8006 BAY 6096 May 2025
Potent and selective adrenergic α2B antagonist

Free Acid Janelia Fluor® Dyes

Cat. No. Product Name / Activity Date Added
8915 Janelia Fluor® 646, free acid Apr 2025
Red dye (Reactive group: free acid). Application: flow cytometry, confocal microscopy, super resolution microscopy (SRM) including dSTORM & STED. Suitable for live cell imaging

ADAMs

Cat. No. Product Name / Activity Date Added
8826 BAY 9835 Jul 2025
Potent ADAMTS7 and ADAMTS12 inhibitor

Biochemicals and Molecular Biology

Cat. No. Product Name / Activity Date Added
8142 DBIA Sep 2025
Chemoproteomic reagent, binds with reactive cysteines and labels with desthiobiotin
8911 ImmunoFect STAR™ Antibody Transfection Reagent May 2025
Reagent capable of efficiently delivering functional antibodies into the cytosol of cells
8869 ArMan Apr 2025
DC-SIGN ligand used to target dendritic cells
8888 LaKe Apr 2025
Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells

BromoCatch Platform

Cat. No. Product Name / Activity Date Added
8940 BromoCatch™ Ligand, Alkyne Sep 2025
Clickable alkyne-functionalized covalent probe for BromoCatch-tagged proteins
8937 Janelia Fluor® 635, BromoCatch™ Ligand Sep 2025
Fluorogenic Janelia Fluor® 635 conjugated covalent ligand for BromoCatch™, enabling no-wash live-cell imaging
7300 BromoCatch™ Control Ligand Sep 2025
Control ligand for use with BromoCatch™, a Self-Labeling Proteins (SLPs) tag platform

Bromodomains

Cat. No. Product Name / Activity Date Added
8892 CCS 1477 Aug 2025
Selective p300/CBP bromodomain inhibitor

Cereblon Targeting Ligands Plus Linkers

Cat. No. Product Name / Activity Date Added
8848 Lenalidomide 5'-piperazine-7'-methoxy Apr 2025
Cereblon ligand with terminal piperazine for onward chemistry

Class I HDACs

Cat. No. Product Name / Activity Date Added
8811 ESI 1 Apr 2025
Selective HDAC3 inhibitor; also myelination inducer

Other Degraders

Cat. No. Product Name / Activity Date Added
7964 hCAII Degrader 11 Mar 2025
Potent human carbonic anhydrase II Degrader (PROTAC®)

Kinase Degraders

Cat. No. Product Name / Activity Date Added
8951 NX 2127 Sep 2025
Potent BTK Degrader (PROTAC®)

Other Degraders

Cat. No. Product Name / Activity Date Added
8854 KL 465 Mar 2025
MAGE-A3 Degrader (PROTAC®)
8891 CRBN5-SNAP2-1C-PIP Mar 2025
Degrader (PROTAC®) of SNAP-tag™ labeled fusion proteins
8890 VHL-SNAP2-5C Mar 2025
Degrader (PROTAC®) of SNAP-tag™ labeled fusion proteins
8833 AZ 3137 Aug 2025
Potent and selective AR and AR L702H Degrader, orally bioavailable

Histone Demethylases

Cat. No. Product Name / Activity Date Added
8128 GSK 2879552 Sep 2025
Lysine-Specific Demethylase 1 (LSD1) inhibitor

ROS and Other Gaseous Donors

Cat. No. Product Name / Activity Date Added
7949 MitoBoronic acid Jul 2025
Ratiometric mass spectrometry mitochondrial hydrogen peroxide (H2O2) probe

Other Fluorescent Dyes

Cat. No. Product Name / Activity Date Added
8935 NucleoLIVE™ Non-Toxic Dye Sep 2025
Ready-to-use fluorescent nuclear stain for live cell imaging, cell toxicity, viability and morphology of 2D and 3D cell cultures
8936 MortaLIVE™ Non-Toxic Dye Sep 2025
Ready-to-use fluorescent live-dead cell stain for long term live cell imaging
8934 ChromaLIVE™ Non-Toxic Dye Sep 2025
Ready-to-use fluorescent probe for long term high content phenotypic screening of live cells

Photoactivatable Janelia Fluor® Dyes

Cat. No. Product Name / Activity Date Added
8132 PA Janelia Fluor® 549, Maleimide Jun 2025
Yellow photoactivatable dye (Reactive group: maleimide). Application: flow cytometry, confocal microscopy, super-resolution microscopy including dSTORM & STED. Suitable for live cell imaging

Endocytosis

Cat. No. Product Name / Activity Date Added
8829 TransMoDE 3 Biotin May 2025
Biotinylated angiopep-2, induces internalization and degradation of streptavidin in brain cell lines

Other Fluorescent Probes

Cat. No. Product Name / Activity Date Added
8110 BI 2852 FL Apr 2025
Pan RAS Tracer
8086 Acridonylalanine Apr 2025
Fluorescent unnatural amino acid.

Functionalized Warhead Ligands

Cat. No. Product Name / Activity Date Added
8827 (+)-JQ1 bump-N, acid functionalized Aug 2025
Negative control for (+)-JQ1 bump, acid functionalized (Cat. No. 7689)

Molecular Glues

Cat. No. Product Name / Activity Date Added
8875 VVD 065 Aug 2025
Covalent allosteric NRF2 inhibitor

Hippo and YAP/TAZ Signaling

Cat. No. Product Name / Activity Date Added
8176 VT 104 Jun 2025
Potent pan-TEAD inhibitor

Other Ion Pumps/Transporters

Cat. No. Product Name / Activity Date Added
8057 V 9302 hydrochloride Mar 2025
ASCT2 (SLC1A5) inhibitor

Rho-Kinases

Cat. No. Product Name / Activity Date Added
7881 CHDI 00580985 Mar 2025
Potent and selective ROCK inhibitor; orally bioavailable and brain penetrant

Kinesin

Cat. No. Product Name / Activity Date Added
5109 SB 743921 hydrochloride May 2025
Potent kinesin spindle protein (KSP) inhibitor

Self-labeling Tags

Cat. No. Product Name / Activity Date Added
8814 PA Janelia Fluor® 549, Haloalkane Jul 2025
Photoactivatable Janelia Fluor® 549 with haloalkane for labeling HaloTag fusion proteins

LDL Receptors

Cat. No. Product Name / Activity Date Added
8828 Angiopep-2 May 2025
Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB

Lipid Nanoparticles

Cat. No. Product Name / Activity Date Added
8909 SM 102 Apr 2025
Cationic ionizable lipid
8902 Angiopep-2-Cys May 2025
Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB
8904 Cys-T7 Peptide May 2025
Targeting peptide for the transferrin receptor (N-term Cys)
8903 RVG29-Cys May 2025
Nicotinic acetylcholine receptor targeting peptide for neuronal delivery
8895 DLin-KC2-DMA Apr 2025
Ionizable cationic lipid

NUAKs

Cat. No. Product Name / Activity Date Added
8914 UCB 9386 Aug 2025
Potent and selective CNS penetrant NUAK1 inhibitor

Organoids

Cat. No. Product Name / Activity Date Added
8853 RS 246204 May 2025
R-Spondin-1 substitute used to initiate small intestinal organoids

Pregnane X Receptors

Cat. No. Product Name / Activity Date Added
8839 SJPYT 310 May 2025
Potent and selective PXR antagonist